Microbial production of 1α-hydroxyvitamin D3 from vitamin D3
| Author | Ahmed, Safwat A. |
| Author | Mesbah, Mostafa K. |
| Author | Youssef, Diaa T. |
| Author | Khalifa, Sherief I. |
| Available date | 2016-03-09T14:00:55Z |
| Publication Date | 2014-01 |
| Publication Name | Natural Product Research |
| Resource | Scopus |
| Citation | Ahmed, S.A., Mesbah, M.K., Youssef, D.T., Khalifa, S.I. "Microbial production of 1α-hydroxyvitamin D3 from vitamin D3" (2014) Natural Product Research, 28 (7), pp. 444-448. |
| ISSN | 1478-6419 |
| Abstract | The microbial transformation of vitamin D3 (1) by the fungi Candida maltosa R42 and Botrytis allii NRRL 2502 was investigated. Incubation of compound 1 with C. maltosa R42 and B. allii NRRL 2502 produced the same three more polar metabolites in small yields. The main metabolite was identified as 1α-hydroxyvitamin D3 (2). This biotransformation has utility as a possible tool for the production of 1α-hydroxyvitamin D3 from the readily available vitamin D3 for patients with compromised kidney function. |
| Language | en |
| Publisher | Taylor and Francis Ltd. |
| Subject | Botrytis allii NRRL 2502 Candida maltosa R42 Renal failure |
| Type | Article |
| Pagination | 444-448 |
| Issue Number | 7 |
| Volume Number | 28 |
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Pharmacy Research [1357 items ]