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Soft biodegradable elastomers based on poly (octanediol-tartarate) for drug delivery and tissue engineering: Synthesis, characterization and biocompatibility studies
(
Taylor & Francis
, 2011 , Article)
The synthesis, characterization and cytocompatibility of amorphous poly (octanediol-tartarate) thermoset biodegradable elastomeric polyesters are reported. The synthesis was achieved by preparing an aliphatic saturated ...
Percutaneous Mitral-Valve Intervention for Secondary Mitral Regurgitation: Data From Real-Life
(
Elsevier
, 2023 , Article Review)
Many questions were raised due to the divergent results between cardiovascular outcomes assessment of the MitraClip percutaneous therapy for heart failure patients with functional mitral regurgitation (COAPT) and multicenter ...
Shrinking the battlefield in cancer therapy: Nanotechnology against cancer stem cells
(
Elsevier
, 2023 , Article)
Cancer remains one of the leading causes of mortality worldwide, presenting a significant healthcare challenge owing to the limited efficacy of current treatments. The application of nanotechnology in cancer treatment ...
Optimizing polypharmacy management in the elderly: a comprehensive European benchmarking survey and the development of an innovative online benchmarking application
(
Frontiers Media
, 2023 , Article)
Background: Polypharmacy, defined as the simultaneous use of multiple medications by a patient, is a worldwide problem of rising prevalence. Paving the way for drug interactions, adverse drug reactions and non-adherence, ...
Drug-Eluting Sutures by Hot-Melt Extrusion: Current Trends and Future Potentials
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2023 , Article Review)
Surgical site infections (SSIs) may result from surgical procedures requiring a secondary administration of drugs at site or systemically in treating the infection. Drug-eluting sutures containing antimicrobial agents ...
Obesity Paradox among Heart Failure with Reduced Ejection Fraction Patients: A Retrospective Cohort Study
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2022 , Article)
Background and Objectives: There is consensus on the negative effects of obesity on the development of heart failure. However, several studies have suggested that obesity may have paradoxical survival benefits in heart ...
Deciphering the complexities of cancer cell immune evasion: Mechanisms and therapeutic implications
(
Elsevier
, 2023 , Article Review)
Cancer immune evasion is one of the principal mechanisms leading to the progression and metastatization of the disease. Despite the migration and infiltration at the tumor site of immune cells, multiple factors can influence ...
Network pharmacology, molecular simulation, and binding free energy calculation-based investigation of Neosetophomone B revealed key targets for the treatment of cancer
(
Frontiers Media SA
, 2024 , Article)
In the current study, Neosetophomone B (NSP-B) was investigated for its anti-cancerous potential using network pharmacology, quantum polarized ligand docking, molecular simulation, and binding free energy calculation. Using ...
Perceptions of Yemeni physicians about sources of drug information and factors predicting their choices
(
Open Science Publishers LLP
, 2021 , Article)
High-quality information is a necessary prerequisite for an optimum prescribing decision that enhances patient healthcare outcomes. Therefore, the purpose of this study was to identify the main sources of information used ...
Evaluation of the impact of COVID-19 pandemic on hospital-acquired infections in a tertiary hospital in Malaysia
(
BioMed Central Ltd
, 2023 , Article)
Background: Infection prevention measures are the gold standard for preventing the spread of hospital-acquired infections (HAIs). COVID-19 pandemic caused major disruptions in infection prevention measures, and this has ...