College of Pharmacy: المرسلات الحديثة
السجلات المعروضة 201 -- 220 من 1384
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Status of Polymer Fused Deposition Modeling (FDM)-Based Three-Dimensional Printing (3DP) in the Pharmaceutical Industry
( Multidisciplinary Digital Publishing Institute (MDPI) , 2024 , Article Review)Additive manufacturing (AM) or 3D printing (3DP) is arguably a versatile and more efficient way for the production of solid dosage forms such as tablets. Of the various 3DP technologies currently available, fused deposition ... -
Network pharmacology, molecular simulation, and binding free energy calculation-based investigation of Neosetophomone B revealed key targets for the treatment of cancer
( Frontiers Media SA , 2024 , Article)In the current study, Neosetophomone B (NSP-B) was investigated for its anti-cancerous potential using network pharmacology, quantum polarized ligand docking, molecular simulation, and binding free energy calculation. Using ... -
Human antigen R: Exploring its inflammatory response impact and significance in cardiometabolic disorders
( Wiley , 2024 , Article Review)RNA-binding proteins (RBPs) play a crucial role in the regulation of posttranscriptional RNA networks, which can undergo dysregulation in many pathological conditions. Human antigen R (HuR) is a highly researched RBP that ... -
The effect of novel nitrogen-based chalcone analogs on colorectal cancer cells: Insight into the molecular pathways
( Elsevier , 2024 , Article)In colorectal cancer (CRC), aberrations in KRAS are associated with aggressive tumorigenesis and an overall low survival rate because of chemoresistance and adverse effects. Ergo, complementary, and integrative medicines ... -
Monoamine oxidase inhibitors extracted from tobacco smoke as neuroprotective factors for potential treatment of Parkinson’s disease
( Bentham Science Publishers B.V. , 2015 , Article)Parkinson’s disease (PD) is a neurodegenerative disease characterized by the loss of mainly the nigrostriatal dopaminergic neurons, which leads to motor dysfunction. Although, most of the drugs are currently used for ... -
Structure-activity relationship investigation of methoxy substitution on anticancer pyrimido[4,5-c]quinolin-1(2H)-ones
(2013 , Article)Pyrimido[4,5-c]quinolin-1(2H)-one derivatives were shown to exert interesting biological activities including anticancer, antimicrobial, and cardiovascular. Substitution with methoxy groups played a crucial role in the ... -
Forging the Path to Precision Medicine in Qatar: A Public Health Perspective on Pharmacogenomics Initiatives
( Frontiers Media , 2024 , Article Review)Pharmacogenomics (PGx) is an important component of precision medicine that promises tailored treatment approaches based on an individual’s genetic information. Exploring the initiatives in research that help to integrate ... -
Redesigning the clinical pharmacy practice model at a psychiatric hospital
( Allen Press Inc. , 2015 , Article)Introduction: Integrated, patient-centered clinical pharmacy services have been shown to improve patient outcomes in a variety of settings, including mental health. In this article, we describe and report the impact of a ... -
Societal health and economic burden of cardiovascular diseases in the population with type 2 diabetes in Qatar. A 10-year forecasting model
( Wiley-Blackwell , 2023 , Article)Aims: To predict the future health and economic burden of cardiovascular disease (CVD) in type 2 diabetes (T2D) in Qatar. Materials and Methods: A dynamic multistate model was designed to simulate the progression of fatal ... -
Beta-blocker therapy in heart failure with preserved ejection fraction (B-HFpEF): A systematic review and meta-analysis
( Elsevier Inc. , 2024 , Article)Introduction: While beta-blockers are considered the cornerstone of treatment for heart failure with reduced ejection fraction, the same may not apply to patients with heart failure with preserved ejection fraction (HFpEF). ... -
Correction to: Developing Leadership Skills in Pharmacy Education
( Springer Nature , 2023 , Article)The article “Developing Leadership Skills in Pharmacy Education” was originally published electronically on the publisher’s internet portal on 22 March 2022 with an error in the author group. The family name of the third ... -
The effectiveness and safety of palbociclib and ribociclib in stage IV HR+/HER-2 negative breast cancer: a nationwide real world comparative retrospective cohort study
( Frontiers Media SA , 2023 , Article)Introduction: Palbociclib and ribociclib are indicated in the first-line treatment of hormonal receptor-positive HER-2 negative (HR+/HER2- negative) advanced breast cancer. Although randomized-controlled trials (RCTs) ... -
Emergency pharmacy workforce views and experience related to the provision of pharmaceutical care during mass gathering events: the FIFA World Cup Qatar 2022™ experience
( Frontiers Media SA , 2023 , Article)Purpose: This study aimed to explore emergency pharmacy workforce perspectives and experiences in providing pharmaceutical care during mass gathering events (i.e., FIFA World Cup Qatar 2022™). Methods: A qualitative ... -
Application of behavioural theories, models, and frameworks in pharmacy practice research based on published evidence: a scoping review
( Springer Science and Business Media Deutschland GmbH , 2024 , Article Review)Background: Pharmacy practice research often focuses on the design, implementation and evaluation of pharmacy services and interventions. The use of behavioural theory in intervention research allows understanding of ... -
Drug-Eluting Sutures by Hot-Melt Extrusion: Current Trends and Future Potentials
( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article Review)Surgical site infections (SSIs) may result from surgical procedures requiring a secondary administration of drugs at site or systemically in treating the infection. Drug-eluting sutures containing antimicrobial agents ... -
Docetaxel-Loaded Methoxy poly(ethylene glycol)-poly (L-lactic Acid) Nanoparticles for Breast Cancer: Synthesis, Characterization, Method Validation, and Cytotoxicity
( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)This study aimed to synthesize and characterize DTX-mPEG-PLA-NPs along with the development and validation of a simple, accurate, and reproducible method for the determination and quantification of DTX in mPEG-PLA-NPs. The ... -
Correction to: Beta-Caryophyllene Exhibits Anti-Proliferative Effects through Apoptosis Induction and Cell Cycle Modulation in Multiple Myeloma Cells (Cancers, (2021), 13, 22, (5741), 10.3390/cancers13225741)
( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)In the original publication [1], errors were identified in the published Figures 4 and 7. The original raw data of western blots could not be retrieved and therefore the experiments were redone to generate the corrected ... -
Exploring the in vivo anti-cancer potential of Neosetophomone B in leukemic cells using a zebrafish xenograft model
( Elsevier Inc. , 2024 , Article)Neosetophomone B (NSP–B) is a unique meroterpenoid fungal secondary metabolite that has previously demonstrated promising anti-cancer properties against various cancer cell lines in vitro. However, its in vivo anti-cancer ... -
Nanoparticle-based materials in anticancer drug delivery: Current and future prospects
( Elsevier , 2023 , Article Review)The past decade has witnessed a breakthrough in novel strategies to treat cancer. One of the most common cancer treatment modalities is chemotherapy which involves administering anti-cancer drugs to the body. However, these ... -
In vitro evaluation of Neosetophomone B inducing apoptosis in cutaneous T cell lymphoma by targeting the FOXM1 signaling pathway
( Elsevier , 2023 , Article)Background: Cutaneous T cell lymphoma (CTCL) is a T cell-derived non-Hodgkin lymphoma primarily affecting the skin, with treatment posing a significant challenge and low survival rates. Objective: In this study, we ...
