تصفح Biomedical Research Center Research حسب المؤلف "Alser, Maha"
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Adaptation of a Mice Doppler Echocardiography Platform to Measure Cardiac Flow Velocities for Embryonic Chicken and Adult Zebrafish.
Benslimane, Fatiha M; Alser, Maha; Zakaria, Zain Z; Sharma, Anju; Abdelrahman, Hana A; Yalcin, Huseyin C... more authors ... less authors ( Frontiers Media , 2019 , Article)Ultrasonography is the most widely used imaging technique in cardiovascular medicine. In this technique, a piezoelectric crystal produces, sends, and receives high frequency ultrasound waves to the body to create an image ... -
Blood Flow Disturbance and Morphological Alterations Following the Right Atrial Ligation in the Chick Embryo.
Alser, Maha; Salman, Huseyin Enes; Naïja, Azza; Seers, Thomas Daniel; Khan, Talha; Yalcin, Huseyin Cagatay... more authors ... less authors ( Frontiers Media , 2022 , Article)Collectively known as congenital heart defects (CHDs), cardiac abnormalities at birth are the most common forms of neonatal defects. Being principally responsible for the heart's pumping power, ventricles are particularly ... -
Effect of left atrial ligation-driven altered inflow hemodynamics on embryonic heart development: clues for prenatal progression of hypoplastic left heart syndrome.
Salman, Huseyin Enes; Alser, Maha; Shekhar, Akshay; Gould, Russell A; Benslimane, Fatiha M; Butcher, Jonathan T; Yalcin, Huseyin C... more authors ... less authors ( Springer , 2021 , Article)Congenital heart defects (CHDs) are abnormalities in the heart structure present at birth. One important condition is hypoplastic left heart syndrome (HLHS) where severely underdeveloped left ventricle (LV) cannot support ... -
From an Apple to a Pear: Moving Fat around for Reversing Insulin Resistance.
Alser, Maha; Elrayess, Mohamed A ( MDPI , 2022 , Article Review)Type 2 diabetes (T2D) is a chronic condition where the body is resistant to insulin, leading to an elevated blood glucose state. Obesity is a main factor leading to T2D. Many clinical studies, however, have described a ... -
In Vitro and In Vivo Validation of GATA-3 Suppression for Induction of Adipogenesis and Improving Insulin Sensitivity
Al-Jaber, Hend; Mohamed, Nura A.; Govindharajan, Vijay K.; Taha, Samir; John, Jomon; Halim, Sharique; Alser, Maha; Al-Muraikhy, Shamma; Anwardeen, Najeha Rizwana; Agouni, Abdelali; Elhissi, Abdelbary; Al-Naemi, Hamda A.; Al-Mansoori, Layla; Elrayess, Mohamed A.... more authors ... less authors ( MDPI , 2022 , Article)Impaired adipogenesis is associated with the development of insulin resistance and an increased risk of type 2 diabetes (T2D). GATA Binding Protein 3 (GATA3) is implicated in impaired adipogenesis and the onset of insulin ... -
Mechanosensitive Pathways in Heart Development: Findings from Chick Embryo Studies.
Alser, Maha; Shurbaji, Samar; Yalcin, Huseyin C ( MDPI , 2021 , Article)The heart is the first organ that starts to function in a developing embryo. It continues to undergo dramatic morphological changes while pumping blood to the rest of the body. Genetic regulation of heart development is ... -
Nitric Oxide Releasing Hydrogel Nanoparticles Decreases Epithelial Cell Injuries Associated With Airway Reopening.
Shurbaji, Samar; El-Sherbiny, Ibrahim M; Alser, Maha; Ali, Isra H; Kordi, Haya; Al-Sadi, Ameena; Popelka, Anton; Benslimane, Fatiha; Yacoub, Magdi; Yalcin, Huseyin C... more authors ... less authors ( Frontiers , 2021 , Article)Acute respiratory distress syndrome (ARDS) is an acute inflammatory lung condition. It is characterized by disruption of gas exchange inside the alveoli, accumulation of protein edema, and an increase in lung stiffness. ...