تصفح Biomedical Research Center Research حسب المؤلف "Al-Thani, Asmaa"
-
Improving Influenza Vaccination Rate among Primary Healthcare Workers in Qatar
Elawad, Khalid H; Farag, Elmoubasher A; Abuelgasim, Dina A; Smatti, Maria K; Al-Romaihi, Hamad E; Al Thani, Mohammed; Al Mujalli, Hanan; Shehata, Zienab; Alex, Merin; Al Thani, Asmaa A; Yassine, Hadi M... more authors ... less authors ( MDPI , 2017 , Article)The purpose of this study was to improve influenza vaccination, and determine factors influencing vaccine declination among health care workers (HCW) in Qatar. We launched an influenza vaccination campaign to vaccinate ... -
Improving influenza vaccination rate among primary healthcareworkers in Qatar
Elawad, Khalid H.; Farag, Elmoubasher A.; Abuelgasim, Dina A.; Smatti, Maria K.; Al-Romaihi, Hamad E.; Al Thani, Mohammed; Al Mujalli, Hanan.; Shehata, Zienab; Alex, Merin; Al Thani, Asmaa A.; Yassine, Hadi M.... more authors ... less authors ( MDPI AG , 2017 , Article)The purpose of this study was to improve influenza vaccination, and determine factors influencing vaccine declination among health care workers (HCW) in Qatar. We launched an influenza vaccination campaign to vaccinate ... -
Inter-Versus Intra-Host Sequence Diversity of pH1N1 and Associated Clinical Outcomes
Al Khatib, Hebah A.; Al Maslamani, , Muna A.; V. Coyle, Peter; Thompson, I. Richard Thompson; A. Farag, Elmoubasher; Al Thani, Asmaa A.; M. Yassine, Hadi... more authors ... less authors ( MDPI , 2020 , Article)The diversity of RNA viruses dictates their evolution in a particular host, community or environment. Here, we reported within- and between-host pH1N1virus diversity at consensus and sub-consensus levels over a three-year ... -
Level of Maternal Respiratory Syncytial Virus (RSV) F Antibodies in Hospitalized Children and Correlates of Protection.
Taleb, Sara A; Al-Ansari, Khalid; Nasrallah, Gheyath K; Elrayess, Mohamed A; Al-Thani, Asmaa A; Derrien-Colemyn, Alexandrine; Ruckwardt, Tracy J; Graham, Barney S; Yassine, Hadi M... more authors ... less authors (2021)RSV is a major cause of lower respiratory infections among children, where no vaccine is available. The stabilized form of the fusion (F) protein, pre-F, is a leading vaccine candidate targeting different populations, ... -
Measuring influenza hemagglutinin (HA) stem-specific antibody-dependent cellular cytotoxicity (ADCC) in human sera using novel stabilized stem nanoparticle probes
Smatti, Maria K.; Nasrallah, Gheyath K.; Al Thani, Asmaa A.; Yassine, Hadi M. ( Elsevier , 2019 , Article)BackgroundGenerating vaccine that confers a complete protection is a major goal in designing a universal influenza vaccine. Currently, there is a considerable interest in the broadly neutralizing antibodies (bnAb) targeting ... -
Mixed Viral-Bacterial Infections and Their Effects on Gut Microbiota and Clinical Illnesses in Children.
Mathew, Shilu; Smatti, Maria K; Al Ansari, Khalid; Nasrallah, Gheyath K; Al Thani, Asmaa A; Yassine, Hadi M... more authors ... less authors ( Nature Research , 2019 , Article)Acute gastroenteritis remains a major cause of morbidity and mortality among young children worldwide. It accounts for approximately 1.34 million deaths annually in children younger than five years. Infection can be caused ... -
Molecular and biological characterization of influenza A viruses isolated from human fecal samples
Al Khatib, Hebah A.; Coyle, Peter V.; Al Maslamani, Muna A.; Al Thani, Asmaa A.; Pathan, Sameer A.; Yassine, Hadi M.... more authors ... less authors ( Elsevier , 2021 , Article)Human influenza viruses are occasionally detected in the stools of influenza patients. Objectives: Here, we investigated the molecular and biological characteristics of intestinal influenza viruses and their potential role ... -
Molecular and Peritoneal Microvascular Changes Cause Peritoneal Membrane Dysfunction by Uremia-Related Mechanisms
Zakaria, El-Rasheid; Tsakou, Magdalini; Prabhu, Kirti S.; Sartaj, Faheem; Al-Thani, Asmaa; Kuttikrishnan, Shilpa; Mohammad, Ramzi M; Khan, Shahab Uddin; Shuaib, Ashfaq... more authors ... less authors ( Hamad bin Khalifa University Press (HBKU Press) , 2016 , Conference Paper)Long-term peritoneal dialysis (PD) is associated with distinct peritoneal structural changes characterized by thickening of the sub-mesothelial cell layer, fibrosis and angiogenesis. These changes were assumed to be the ... -
Molecular characterization of extended spectrum β -lactamases enterobacteriaceae causing lower urinary tract infection among pediatric population.
Eltai, Nahla O; Al Thani, Asmaa A; Al-Ansari, Khalid; Deshmukh, Anand S; Wehedy, Eman; Al-Hadidi, Sara H; Yassine, Hadi M... more authors ... less authors ( BioMed Central , 2018 , Article)The β-lactam antibiotics have traditionally been the main treatment of Enterobacteriaceae infections, nonetheless, the emergence of species producing β- Lactamases has rendered this class of antibiotics largely ineffective. ... -
Predictive Biomarkers of Intensive Care Unit and Mechanical Ventilation Duration in Critically-Ill Coronavirus Disease 2019 Patients.
Taleb, Sara; Yassine, Hadi M; Benslimane, Fatiha M; Smatti, Maria K; Schuchardt, Sven; Albagha, Omar; Al-Thani, Asmaa A; Ait Hssain, Ali; Diboun, Ilhame; Elrayess, Mohamed A... more authors ... less authors ( Frontiers Media , 2021 , Article)Detection of early metabolic changes in critically-ill coronavirus disease 2019 (COVID-19) patients under invasive mechanical ventilation (IMV) at the intensive care unit (ICU) could predict recovery patterns and help in ... -
Prevalence and Phylogenetic Analysis of Parvovirus (B19V) among Blood Donors with Different Nationalities Residing in Qatar
Abdelrahman, Doua; Al-Sadeq, Duaa W.; Smatti, Maria K.; Taleb, Sara A.; AbuOdeh, Raed O.; Al-Absi, Enas S.; Al-Thani, Asmaa A.; Coyle, Peter. V.; Al-Dewik, Nader; Al Qahtani, Ahmed A.; Yassine, Hadi M.; Nasrallah, Gheyath K.... more authors ... less authors ( MDPI , 2021 , Article)Human parvovirus (B19V) is the causative agent of erythema infectiosum in children and is linked to a wide range of clinical manifestations. Studies related to B19V prevalence in the Middle East and North Africa (MENA) ... -
Prevalence of antibiotic resistant Escherichia coli isolates from fecal samples of food handlers in Qatar
Eltai, Nahla O; Yassine, Hadi M.; Al Thani, Asmaa A.; Abu Madi, Marwan A.; Ismail, Ahmed; Doiphode, S; Alalia, Walid Q... more authors ... less authors ( BioMed Central , 2018 , Article)Background: It is well documented that food handlers harbor and shed enteric foodborne pathogens causing foodborne disease outbreaks. However, little known on enteric antibiotic resistant (AR) bacteria carriage in ... -
Prevalence of antibiotic resistant Escherichia coli isolates from local and imported retail chicken carcasses.
Eltai, Nahla; Yassine, Hadi; El-Obeid, Tahra; Al-Hadidi, Sara; Al Thani, Asmaa; Alali, Walid... more authors ... less authors ( International Association for Food Protection , 2020 , Article)The spread of antibiotic resistance has been associated with consumption of food contaminated with pathogenic and non-pathogenic resistant bacteria. The objective of this study was to determine the prevalence of antibiotic ... -
Profiling of intestinal microbiota in patients infected with respiratory influenza a and b viruses
Al Khatib, Hebah A.; Mathew, Shilu; Smatti, Maria K.; Eltai, Nahla O.; Pathan, Sameer A.; Al Thani, Asmaa A.; Coyle, Peter V.; Al Maslamani, Muna A.; Yassine, Hadi M.... more authors ... less authors ( MDPI , 2021 , Article)Little is known about the association between respiratory viral infections and their impact on intestinal microbiota. Here, we compared the effect of influenza types, A and B, and influenza shedding in patients’ stools on ... -
Pseudomonas aeruginosa: arsenal of resistance mechanisms, decades of changing resistance profiles, and future antimicrobial therapies.
El Zowalaty, Mohamed E.; Al Thani, Asmaa A.; Webster, Thomas J.; El Zowalaty, Ahmed E.; Schweizer, Herbert P.; Nasrallah, Gheyath K.; Marei, Hany E.; Ashour, Hossam M.... more authors ... less authors ( Future Medicine , 2015 , Article)Antimicrobial resistance is one of the most serious public health issues facing humans since the discovery of antimicrobial agents. The frequent, prolonged, and uncontrolled use of antimicrobial agents are major factors ... -
Reinfections in COVID-19 Patients: Impact of Virus Genetic Variability and Host Immunity
Fakhroo, Aisha; AlKhatib, Hebah A; Al Thani, Asmaa A; Yassine, Hadi M ( MDPI , 2021 , Article)The COVID-19 pandemic is still posing a devastating threat to social life and economics. Despite the modest decrease in the number of cases during September-November 2020, the number of active cases is on the rise again. ... -
The Spectrum of Antibiotic Prescribing During COVID-19 Pandemic: A Systematic Literature Review
Al-Hadidi, Sara H.; Alhussain, Hashim; Abdel Hadi, Hamad; Johar, Alreem; Yassine, Hadi M.; Al Thani, Asmaa A.; Eltai, Nahla O.... more authors ... less authors ( Mary Ann Liebert , 2021 , Article Review)Objectives: Over the last decades, there has been a significant increase in antimicrobial prescribing and consumption associated with the development of patients’ adverse events and antimicrobial resistance (AMR) to the ... -
Viral-Induced Enhanced Disease Illness
Smatti, Maria K; Al Thani, Asmaa A; Yassine, Hadi M ( Frontiers Media , 2018 , Article)Understanding immune responses to viral infections is crucial to progress in the quest for effective infection prevention and control. The host immunity involves various mechanisms to combat viral infections. Under certain ... -
Viruses and Autoimmunity: A Review on the Potential Interaction and Molecular Mechanisms.
Smatti, Maria K; Cyprian, Farhan S; Nasrallah, Gheyath K; Al Thani, Asmaa A; Almishal, Ruba O; Yassine, Hadi M... more authors ... less authors ( MDPI , 2019 , Article)For a long time, viruses have been shown to modify the clinical picture of several autoimmune diseases, including type 1 diabetes (T1D), systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), Sjögren's syndrome ... -
Whole-Genome Sequencing for Molecular Characterization of Carbapenem-Resistant Enterobacteriaceae Causing Lower Urinary Tract Infection among Pediatric Patients
Al Mana, Hassan; Sundararaju, Sathyavathi; Tsui, Clement K. M.; Perez-Lopez, Andres; Yassine, Hadi; Al Thani, Asmaa; Al-Ansari, Khalid; Eltai, Nahla O... more authors ... less authors ( MDPI , 2021 , Article)Antibiotic resistance is a growing public health problem globally, incurring health and cost burdens. The occurrence of antibiotic-resistant bacterial infections has increased significantly over the years. Gram-negative ...