Browsing Biomedical Research Center Research by Author "n 2012188483"
Now showing items 1-5 of 5
-
Genome-Wide Association Study Reveals a Novel Association Between MYBPC3 Gene Polymorphism, Endurance Athlete Status, Aerobic Capacity and Steroid Metabolism.
Al-Khelaifi, Fatima; Yousri, Noha A; Diboun, Ilhame; Semenova, Ekaterina A; Kostryukova, Elena S; Kulemin, Nikolay A; Borisov, Oleg V; Andryushchenko, Liliya B; Larin, Andrey K; Generozov, Edward V; Miyamoto-Mikami, Eri; Murakami, Haruka; Zempo, Hirofumi; Miyachi, Motohiko; Takaragawa, Mizuki; Kumagai, Hiroshi; Naito, Hisashi; Fuku, Noriyuki; Abraham, David; Hingorani, Aroon; Donati, Francesco; Botrè, Francesco; Georgakopoulos, Costas; Suhre, Karsten; Ahmetov, Ildus I; Albagha, Omar; Elrayess, Mohamed A... more authors ... less authors ( Frontiers Media , 2020 , Article)The genetic predisposition to elite athletic performance has been a controversial subject due to the underpowered studies and the small effect size of identified genetic variants. The aims of this study were to investigate ... -
Metabolic profiling of elite athletes with different cardiovascular demand
Al-Khelaifi, Fatima; Donati, Francesco; Botrè, Francesco; Latiff, Aishah; Abraham, David; Hingorani, Aroon; Georgakopoulos, Costas; Suhre, Karsten; Yousri, Noha A; Elrayess, Mohamed A... more authors ... less authors ( John Wiley & Sons Ltd , 2019 , Article)Intensive exercise of elite athletes can lead to physiological alterations in the cardiovascular system in response to increased stroke volume and blood pressure, known collectively as cardiovascular demand (CD). This study ... -
Qatar genome: Insights on genomics from the Middle East
Mbarek, Hamdi; Devadoss Gandhi, Geethanjali; Selvaraj, Senthil; Al-Muftah, Wadha; Badji, Radja; Al-Sarraj, Yasser; Saad, Chadi; Darwish, Dima; Alvi, Muhammad; Fadl, Tasnim; Yasin, Heba; Alkuwari, Fatima; Razali, Rozaimi; Aamer, Waleed; Abbaszadeh, Fatemeh; Ahmed, Ikhlak; Mokrab, Younes; Suhre, Karsten; Albagha, Omar; Fakhro, Khalid; Badii, Ramin; Ismail, Said I.; Althani, Asma... more authors ... less authors ( Wiley , 2022 , Article)Despite recent biomedical breakthroughs and large genomic studies growing momentum, the Middle Eastern population, home to over 400 million people, is underrepresented in the human genome variation databases. Here we ... -
Signal transducer and activator of transcription 3 (Stat3) suppresses stat1/interferon signaling pathway and inflammation in senescent preadipocytes
Madani, Aisha Y.; Majeed, Yasser; Abdesselem, Houari B.; Agha, Maha V.; Vakayil, Muneera; Al Sukhun, Nour K.; Halabi, Najeeb M.; Kumar, Pankaj; Hayat, Shahina; Elrayess, Mohamed A.; Rafii, Arash; Suhre, Karsten; Mazloum, Nayef A.... more authors ... less authors ( MDPI , 2021 , Article)© 2021 by the authors. Licensee MDPI, Basel, Switzerland. Obesity promotes premature aging and dysfunction of white adipose tissue (WAT) through the accumulation of cellular senescence. The senescent cells burden in WAT ... -
Signal Transducer and Activator of Transcription 3 (STAT3) Suppresses STAT1/Interferon Signaling Pathway and Inflammation in Senescent Preadipocytes.
Madani, Aisha Y; Majeed, Yasser; Abdesselem, Houari B; Agha, Maha V; Vakayil, Muneera; Sukhun, Nour K Al; Halabi, Najeeb M; Kumar, Pankaj; Hayat, Shahina; Elrayess, Mohamed A; Rafii, Arash; Suhre, Karsten; Mazloum, Nayef A... more authors ... less authors ( MDPI , 2021 , Article)Obesity promotes premature aging and dysfunction of white adipose tissue (WAT) through the accumulation of cellular senescence. The senescent cells burden in WAT has been linked to inflammation, insulin-resistance (IR), ...