Browsing Biomedical Research Center Research by Publication Date
Now showing items 81-100 of 690
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Seroprevalence of Toxoplasma gondii infection in feral cats in Qatar
( BioMed Central , 2017 , Article)Background: Cats are essential in the life cycle of Toxoplasma gondii as they can shed the environmentally resistant oocysts after acquiring infection. Human populations living in cities with high densities of feral cats ... -
Nanotubes Impregnated Human Olfactory Bulb Neural Stem Cells Promote Neuronal Differentiation in Trimethyltin-induced Neurodegeneration Rat Model
( Wiley , 2017 , Article)Neural stem cells (NSCs) are multipotent self-renewing cells that could be used in cellular-based therapy for a wide variety of neurodegenerative diseases including Alzheimer's diseases (AD), Parkinson's disease (PD), ... -
The Interference of Notch1 target Hes1 affects cell growth, differentiation and invasiveness of glioblastoma stem cells through modulation of multiple oncogenic targets
( Impact Journals , 2017 , Article)The invasive and lethal nature of Glioblastoma multiforme (GBM) necessitates the continuous identification of molecular targets and search of efficacious therapies to inhibit GBM growth. The GBM resistance to chemotherapy ... -
Mesenchymal Stem Cells in the Treatment of Traumatic Brain Injury.
( Frontiers Media , 2017 , Article)Traumatic brain injury (TBI) is characterized by a disruption in the normal function of the brain due to an injury following a trauma, which can potentially cause severe physical, cognitive, and emotional impairment. The ... -
Heart Function and Hemodynamics Analysis for Zebrafish Embryos
( Wiley , 2017 , Article)The zebrafish has emerged to become a powerful vertebrate animal model for cardiovascular research in recent years. Its advantages include easy genetic manipulation, transparency, small size, low cost, and the ability to ... -
Synthesis, characterization, and antimicrobial properties of novel double layer nanocomposite electrospun fibers for wound dressing applications
( Dove Press , 2017 , Article)Herein, novel hybrid nanomaterials were developed for wound dressing applications with antimicrobial properties. Electrospinning was used to fabricate a double layer nanocomposite nanofibrous mat consisting of an upper ... -
Seroprevalence of hepatitis E virus among blood donors in Qatar (2013-2016)
( Wiley , 2017 , Article)BACKGROUND Hepatitis E virus (HEV) is an RNA virus transmitted mainly through zoonotic transmission or fecal–oral route. More than 80% of Qatar's population are expatriates, including many coming from hyperendemic ... -
Chitosan gold nanoparticles for detection of amplified nucleic acids isolated from sputum
( Elsevier , 2017 , Article)A platform for nucleic acid detection employing chitosan and chitosan coated gold nanoparticles (AuNPs) was developed. Mycobacterium tuberculosis (MTB) was used as a model target. MTB DNA was extracted from sputum using ... -
Colorimetric gold nanoparticles-based assay for direct detection of Clostridium difficile in clinical isolates from Qatar
( Academic Journals , 2017 , Article)Clostridium difficile infection (CDI) is a significant health problem worldwide. Control and prevention strategies of C. difficile horizontal transmission require assays with fast detection with high specificity and ... -
Cysteamine revisited: repair of arginine to cysteine mutations.
( Springer Verlag , 2017 , Article)Cysteamine is a small aminothiol endogenously derived from coenzyme A degradation. For some decades, synthetic cysteamine has been employed for the treatment of cystinosis, and new uses of the drug continue to emerge. In ... -
Substantial toxic effect of water-pipe smoking on the early stage of embryonic development
( Oxford University Press , 2017 , Article)Water-pipe smoking (WPS) is the most widespread tobacco use in the Middle-East, and is rapidly spreading globally. Smoke from WP contains most of the compounds present in cigarette smoke, although in different proportions. ... -
Epstein-Barr virus and its association with Fascin expression in colorectal cancers in the Syrian population: A tissue microarray study.
( Taylor & Francis , 2017 , Article)Colorectal cancer (CRC) is the third most common malignancy in both men and women worldwide. Colorectal carcinogenesis is a complex, multistep process involving environmental and lifestyle features as well as sequential ... -
Estimating Seroprevalence of Herpes Simplex Virus Type 1 among Different Middle East and North African Male Populations Residing in Qatar
( Wiley , 2017 , Article)HSV-1 epidemiology in the Middle East and North Africa (MENA) remains poorly understood. Our study aimed to measure HSV-1 antibody prevalence (seroprevalence) and its age-distribution among select MENA populations residing ... -
A single tube system for the detection of Mycobacterium tuberculosis DNA using gold nanoparticles based FRET assay
( Elsevier , 2017 , Article)Abstract The global combat against MTB is limited by challenges in accurate affordable detection. In this study, a rapid, affordable, single tube system for detection of unamplified MTB16s rDNA was developed. Utilizing a ... -
Molecular analysis of the enteric protozoa associated with acute diarrhea in hospitalized children
( Frontiers Media S.A. , 2017 , Article)Pediatric diarrhea is a common cause of death among children under 5 years of age. In the current study, we investigated the frequency of intestinal parasites among 580 pediatric patients with chronic diarrhea. Parasitic ... -
A single tube system for the detection of Mycobacterium tuberculosis DNA using gold nanoparticles based FRET assay
( Elsevier , 2017 , Other)The global combat against MTB is limited by challenges in accurate affordable detection. In this study, a rapid, affordable, single tube system for detection of unamplified MTB16s rDNA was developed. Utilizing a AuNP based ... -
Role of the Gastrointestinal Tract Microbiome in the Pathophysiology of Diabetes Mellitus.
( Hindawi Publishing Corporation , 2017 , Article)The incidence of diabetes mellitus is rapidly increasing throughout the world. Although the exact cause of the disease is not fully clear, perhaps, genetics, ethnic origin, obesity, age, and lifestyle are considered as few ... -
Toxoplasma infection and milk consumption: Meta-analysis of assumptions and evidences.
( Taylor & Francis , 2017 , Article)Toxoplasmosis is the most widespread infection worldwide. It occurs within congenital contamination, organ transplant or immune system depression. Primary infection is mainly foodborne with the ingestion of raw or undercooked ... -
Coproscopy and molecular screening for detection of intestinal protozoa
( BioMed Central , 2017 , Article)Intestinal parasitosis is one of several health concerns about immigrants who travel from endemic to non-endemic regions. Reliable rapid sensitive diagnostic tools, for use in non-endemic regions, are urgently required to ... -
Improving Influenza Vaccination Rate among Primary Healthcare Workers in Qatar
( MDPI , 2017 , Article)The purpose of this study was to improve influenza vaccination, and determine factors influencing vaccine declination among health care workers (HCW) in Qatar. We launched an influenza vaccination campaign to vaccinate ...