Browsing Biomedical Research Center Research by Title

Now showing items 283-302 of 668

    • The genetic basis and the diagnostic yield of genetic testing related to nonsyndromic hearing loss in Qatar 

      Alkhidir, Shaza; El-Akouri, Karen; Al-Dewik, Nader; Khodjet-El-khil, Houssein; Okashah, Sarah; ... more authors ( Springer Nature , 2024 , Article)
      Hearing loss is the most predominant sensory defect occurring in pediatrics, of which, 66% cases are attributed to genetic factors. The prevalence of hereditary hearing loss increases in consanguineous populations, and the ...

    • Genetic Diversity and Prevalence of in Qatar. 

      Chourabi, Marwa; Boughattas, Sonia; Abdallah, Atiyeh M; Ismail, Ahmed; Behnke, Jerzy M; ... more authors ( Frontiers Media , 2021 , Article)
      is a common human intestinal parasite worldwide, and the causative agent of diarrhea, with the severity of disease ranging from asymptomatic to intense and debilitating infection. is known to consist of eight genetically ...

    • Genetic relatedness and host specificity of Pseudomonas aeruginosa isolates from cystic fibrosis and non-cystic fibrosis patients 

      Abdulwahab, Atqah; Taj-Aldeen, Saad J.; Doiphode, S; Abdulla, Shaikha H.; Muhammed, Ramees; ... more authors ( Dove Medical Press Limited , 2014 , Article)
      Background: Pseudomonas aeruginosa is one of the primary pathogens isolated more frequently in cystic fibrosis (CF) and it exhibits innate resistance to a wide range of antibiotics. Purpose: We sought to determine whether ...

    • Genetic Susceptibility to Infectious Diseases in the Qatari Population 

      Smatti, Maria Khalid; Al-Sarraj, Yasser; Albagha, Omar Yassine, Hadi ( Qatar University Press , 2021 , Poster)
      Background: Infectious diseases (IDs) account for 8% of deaths annually in Qatar, and therefore, represent a significant challenge for public health. Interestingly, the spread and severity of viral infections vary considerably ...

    • Genetically unmatched human iPSC and ESC exhibit equivalent gene expression and neuronal differentiation potential. 

      Marei, Hany E; Althani, A; Lashen, S; Cenciarelli, C; Hasan, Anwarul ( Nature Publishing Group , 2017 , Article)
      The potential uniformity between differentiation and therapeutic potential of human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs) remains debatable. We studied the gene expression profiles, ...

    • Genome-wide association study identifies several loci for HEV seropositivity 

      Maria K., Smatti; Al-Sarraj, Yasser A.; Albagha, Omar; Yassine, Hadi M. ( Elsevier , 2023 , Article)
      Hepatitis E viral (HEV) infection imposes a heavy global health burden. The variability in the prevalence of serological markers of HEV infection between different ethnic groups proposes a host genetic influence. Here, we ...

    • Genome-Wide Association Study Reveals a Novel Association Between MYBPC3 Gene Polymorphism, Endurance Athlete Status, Aerobic Capacity and Steroid Metabolism. 

      Al-Khelaifi, Fatima; Yousri, Noha A; Diboun, Ilhame; Semenova, Ekaterina A; Kostryukova, Elena S; ... more authors ( Frontiers Media , 2020 , Article)
      The genetic predisposition to elite athletic performance has been a controversial subject due to the underpowered studies and the small effect size of identified genetic variants. The aims of this study were to investigate ...

    • Geographical distribution of air pollution in Doha Qatar 

      Safi, Mariem; Ali Elobaid, Elnaiem ( Hamad bin Khalifa University Press (HBKU Press) , 2018 , Conference Paper)
      Urban air pollution is an inevitable consequence of the urbanization representing a growing concern to scientists, policymakers and an increasing fraction of the population. Air pollution is an acute problem especially in ...

    • Glioma extracellular vesicles for precision medicine: prognostic and theragnostic application 

      Marei, Hany E.; Althani, Asmaa; Afifi, Nahla; Hasan, Anwarul; Caceci, Thomas; ... more authors ( Springer , 2022 , Article Review)
      EV produced by tumour cells carry a diverse population of proteins, lipids, DNA, and RNA molecules throughout the body and appear to play an important role in the overall development of the disease state, according to ...

    • A Global Declaration on Appropriate Use of Antimicrobial Agents across the Surgical Pathway 

      Sartelli, Massimo; Kluger, Yoram; Ansaloni, Luca; Carlet, Jean; Brink, Adrian; ... more authors ( Mary Ann Liebert , 2017 , Article)
      This declaration, signed by an interdisciplinary task force of 234 experts from 83 different countries with different backgrounds, highlights the threat posed by antimicrobial resistance and the need for appropriate use ...

    • Glycan repositioning of influenza hemagglutinin stem facilitates the elicitation of protective cross-group antibody responses. 

      Boyoglu-Barnum, Seyhan; Hutchinson, Geoffrey B; Boyington, Jeffrey C; Moin, Syed M; Gillespie, Rebecca A; ... more authors ( Nature Research , 2020 , Article)
      The conserved hemagglutinin (HA) stem has been a focus of universal influenza vaccine efforts. Influenza A group 1 HA stem-nanoparticles have been demonstrated to confer heterosubtypic protection in animals; however, the ...

    • Glycine and Folate Ameliorate Models of Congenital Sideroblastic Anemia 

      Fernández-Murray1, J. Pedro; Prykhozhij, Sergey; Dufay, J. Noelia; Steele, Shelby; Gaston, Daniel; ... more authors ( Public Library of Science (USA) , 2016 , Article)
      Sideroblastic anemias are acquired or inherited anemias that result in a decreased ability to synthesize hemoglobin in red blood cells and result in the presence of iron deposits in the mitochondria of red blood cell ...

    • Glycine improves peritoneal vasoreactivity to dialysis solutions in the elderly 

      Zakaria, El Rasheid; Joseph, Bellal; Hamidi, Mohammad; Zeeshan, Muhammad; Algamal, Abdelrahman; ... more authors ( Hamad Medical Corporation , 2019 , Article)
      Background: Peritoneal dialysis solution (PDS) dilates peritoneal microvessels predominantly by the activation of the endothelial nitric oxide (NO) pathway. We made an incidental observation of decreased PDS-induced, ...

    • GOLD NANOPARTICLES-BASED ASSAYS FOR DIRECT AND COST EFFECTIVE DETECTION OF CLOSTRIDIUM DIFFICILE IN QATAR 

      Al-Saadi, Tahani Masoud Saleh (2015 , Master Thesis)
      Background Clostridium difficile Infection (CDI) is one of the common health problems worldwide. Prevention techniques require fast and precise detection with high sensitivity. Conventional diagnostic methods are ...

    • Graphene Oxide Loaded Hydrogel for Enhanced Wound Healing in Diabetic Patients 

      Ur Rehman S.R.; Augustine R.; Zahid A.A.; Ahmed R.; Hasan A. ( Institute of Electrical and Electronics Engineers Inc. , 2019 , Conference Paper)
      Chronic wound or slow healing of a wound is one of the serious complications in diabetic patients. The decrease in the proliferation and migration of cells such as keratinocytes and fibroblasts is the major reason for the ...

    • Growth factor loaded in situ photocrosslinkable poly(3-hydroxybutyrate-co-3-hydroxyvalerate)/gelatin methacryloyl hybrid patch for diabetic wound healing 

      Augustine, Robin; Hasan, Anwarul; Dalvi, Yogesh B.; Rehman, Syed Raza Ur; Varghese, Ruby; ... more authors ( Elsevier , 2021 , Article)
      © 2020 The Authors Management of chronic diabetic ulcers remains as a major challenge in healthcare which requires extensive multidisciplinary approaches to ensure wound protection, management of excess wound exudates and ...

    • Growth factor releasing core-shell polymeric scaffolds for tissue engineering applications 

      Augustine, Robin; Zahid, Alap; Wang, Mian; Webster, Thomas j.; Hasan, Anwarul ( Institute of Electrical and Electronics Engineers Inc. , 2019 , Conference Paper)
      Tissue engineering is the use of a combination of cells, biomaterials and appropriate signals to repair or improve the functions of damaged tissues. Our group is exploiting various approaches to effectively encapsulate ...

    • Haematococcus pluvialis Microalgae Extract Inhibits Proliferation, Invasion, and Induces Apoptosis in Breast Cancer Cells 

      Alateyah, Nouralhuda; Ahmad, Salma M. S.; Gupta, Ishita; Fouzat, Arij; Thaher, Mahmoud Ibrahim; ... more authors ( Frontiers Media S.A. , 2022 , Article)
      Breast cancer (BC) is the most common malignant cancer in females worldwide. Drug resistance, toxicity, and the failure of current therapies to completely cure BC has challenged conventional medicine. Consequently, ...

    • Halloysite nanotubes and halloysite-based composites for biomedical applications 

      Fakhruddin, Khalida; Hassan, Rozita; Aslam Khan, Muhammad Umar; Allisha, Sabrina Naula; Abd Razak, Saiful Izwan; ... more authors ( Elsevier , 2021 , Article)
      Novel biomaterials for diagnostics and therapeutics of biomedical issues have been considered using biomedical science and health care. Halloysite nanotubes (HNTs) are naturally occurring aluminosilicate clay. Because of ...

    • Heart function and hemodynamic analysis for zebrafish embryos 

      Yalcin, Huseyin C.; Amindari, Armin; Butcher, Jonathan T.; Althani, Asma; Yacoub, Magdi ( John Wiley and Sons Inc. , 2017 , Article Review)
      The Zebrafish has emerged to become a powerful vertebrate animal model for cardiovascular research in recent years. Its advantages include easy genetic manipulation, transparency, small size, low cost, and the ability to ...