Browsing Biomedical Research Center Research by Title
Now showing items 311-330 of 528
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M cell targeting engineered biomaterials for effective vaccination
( Elsevier Ltd , 2019 , Article)Vaccines are one of the greatest medical interventions of all time and have been successful in controlling and eliminating a myriad of diseases over the past two centuries. Among several vaccination strategies, mucosal ... -
Materials Against COVID-19: How Materials Science can Impact the Pandemic?
( Emergent Materials Journal - Qatar University , 2020 , Video)This webinar aims to gather scientists, clinicians, and industry experts working on coronavirus (COVID-19). The focus of the event is a variety of material science applications for detection, prevention, and treatment of ... -
Measuring influenza hemagglutinin (HA) stem-specific antibody-dependent cellular cytotoxicity (ADCC) in human sera using novel stabilized stem nanoparticle probes
( Elsevier , 2019 , Article)BackgroundGenerating vaccine that confers a complete protection is a major goal in designing a universal influenza vaccine. Currently, there is a considerable interest in the broadly neutralizing antibodies (bnAb) targeting ... -
Mechanosensitive Pathways in Heart Development: Findings from Chick Embryo Studies.
( MDPI , 2021 , Article)The heart is the first organ that starts to function in a developing embryo. It continues to undergo dramatic morphological changes while pumping blood to the rest of the body. Genetic regulation of heart development is ... -
Mediators of Impaired Adipogenesis in Obesity-Associated Insulin Resistance and T2DM
( IntechOpen , 2019 , Book chapter)Obesity has become a global health issue due to its high prevalence and associated comorbidities including insulin resistance (IR) and type 2 diabetes mellitus (T2DM). Obesity is associated with the expansion of adipose ... -
Mesenchymal Stem Cells in the Treatment of Traumatic Brain Injury.
( Frontiers Media , 2017 , Article)Traumatic brain injury (TBI) is characterized by a disruption in the normal function of the brain due to an injury following a trauma, which can potentially cause severe physical, cognitive, and emotional impairment. The ... -
Metabolic consequences of obesity on the hypercoagulable state of polycystic ovary syndrome.
( Nature Research , 2021 , Article)Polycystic ovary syndrome (PCOS) women have a hypercoagulable state; however, whether this is intrinsically due to PCOS or, alternatively, a consequence of its metabolic complications is unclear. We determined plasma ... -
Metabolic GWAS of elite athletes reveals novel genetically-influenced metabolites associated with athletic performance.
( Nature Research , 2019 , Article)Genetic research of elite athletic performance has been hindered by the complex phenotype and the relatively small effect size of the identified genetic variants. The aims of this study were to identify genetic predisposition ... -
Metabolic profiling of elite athletes with different cardiovascular demand
( John Wiley & Sons Ltd , 2019 , Article)Intensive exercise of elite athletes can lead to physiological alterations in the cardiovascular system in response to increased stroke volume and blood pressure, known collectively as cardiovascular demand (CD). This study ... -
Metabolic profiling of pre-gestational and gestational diabetes mellitus identifies novel predictors of pre-term delivery.
( BMC , 2020 , Article)Pregnant women with gestational diabetes mellitus (GDM) or type 2 diabetes mellitus (T2DM) are at increased risks of pre-term labor, hypertension and preeclampsia. In this study, metabolic profiling of blood samples collected ... -
Metabolic Signature of Leukocyte Telomere Length in Elite Male Soccer Players
( Frontiers Media , 2021 , Article)Biological aging is associated with changes in the metabolic pathways. Leukocyte telomere length (LTL) is a predictive marker of biological aging; however, the underlying metabolic pathways remain largely unknown. The aim ... -
Metabolic signature of obesity-associated insulin resistance and type 2 diabetes.
( BMC , 2019 , Article)Obesity is associated with an increased risk of insulin resistance and type 2 diabetes mellitus (T2DM). However, some obese individuals maintain their insulin sensitivity and exhibit a lower risk of associated comorbidities. ... -
Metabolic Signatures of Type 2 Diabetes Mellitus and Hypertension in COVID-19 Patients With Different Disease Severity.
( Frontiers Media , 2022 , Article)Increased COVID-19 disease severity is higher among patients with type 2 diabetes mellitus and hypertension. However, the metabolic pathways underlying this association are not fully characterized. This study aims to ... -
Metabolomic Profiling of Pregnancies With Polycystic Ovary Syndrome Identifies a Unique Metabolic Signature and Potential Predictive Biomarkers of Low Birth Weight
( Frontiers Media , 2021 , Article)Polycystic ovary syndrome (PCOS) is a complex syndrome with clinical features of an endocrine/metabolic disorder. Various metabolites show significant association with PCOS; however, studies comparing the metabolic profile ... -
Metabolomics and doping analysis: promises and pitfalls.
( Future Science , 2020 , Article)This brief commentary presents an overview of the potential utility of metabolomics-based approaches in doping analysis, with particular emphasis on areas where the current analytical procedures would most benefit from ... -
Metabolomics of lean/overweight insulin resistant females reveals alterations in steroids and fatty acids.
( Endocrine Society , 2020 , Article)The global diabetes epidemic is largely attributed to obesity-triggered metabolic syndrome. However, the impact of insulin resistance (IR) prior to obesity on the high prevalence of diabetes and the molecular mediators ... -
Metabolomics Profiling of Vitamin D Status in Relation to Dyslipidemia
( MDPI , 2022 , Article)Vitamin D deficiency is a global disorder associated with several chronic illnesses including dyslipidemia and metabolic syndrome. The impact of this association with both dyslipidemia and vitamin D deficiency on metabolomics ... -
Metagenomic analysis demonstrates the diversity of the fecal virome in asymptomatic pigs in East Africa
( Springer Vienna , 2016 , Article)Pigs harbor a variety of viruses that are closely related to human viruses and are suspected to have zoonotic potential. Little is known about the presence of viruses in smallholder farms where pigs are in close contact ... -
Microbiome engineering to combat antimicrobial resistance and upsurge productivity of food animals: a systematic review
( CSIRO Publishing , 2022 , Article)Extensive antimicrobial usage in animal farming plays a prominent role in the antimicrobial resistance (AMR) crisis and is repeatedly highlighted as an area needing development under the ‘One Health’ approach. Alternative ... -
Microfluidic-based virus detection methods for respiratory diseases
( Springer , 2021 , Article)With the recent SARS-CoV-2 outbreak, the importance of rapid and direct detection of respiratory disease viruses has been well recognized. The detection of these viruses with novel technologies is vital in timely prevention ...
