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Developmental Toxicity of Surface-Modified Gold Nanorods in the Zebrafish Model
(
American Chemical Society
, 2022 , Article)
Background: nanotechnology is one of the fastest-growing areas, and it is expected to have a substantial economic and social impact in the upcoming years. Gold particles (AuNPs) offer an opportunity for wide-ranging ...
Functional characterization of human myosin-binding protein C3 variants associated with hypertrophic cardiomyopathy reveals exon-specific cardiac phenotypes in zebrafish model
(
Wiley
, 2020 , Article)
© 2020 Wiley Periodicals, Inc. Myosin-binding protein C 3 (MYBPC3) variants are the most common cause of hypertrophic cardiomyopathy (HCM). HCM is a complex cardiac disorder due to its significant genetic and clinical ...
Electrospun polylactic acid/date palm polyphenol extract nanofibres for tissue engineering applications
(
Springer
, 2019 , Article)
In this study, a set of polylactic acid (PLA)/polyphenol extracted from date palm fruit (DP) blends were prepared by electrospinning process to be used as cell culture scaffolds for tissue engineering applications. For ...
Nanotechnology in medicine – our experiences
(
Macedonian Pharmaceutical Association
, 2022 , Article)
The success of design criteria for long-circulating drug delivery systems to support membrane receptor-ligand interaction and internalization has been limited and there is a need to develop smarter approaches for efficient ...
Assessment of calcified aortic valve leaflet deformations and blood flow dynamics using fluid-structure interaction modeling
(
Elsevier
, 2017 , Article)
Aortic valve diseases are among the most common cardiovascular defects. Since a non-functioning valve results in disturbed blood flow conditions, the diagnosis of such defects is based on identification of stenosis via ...
Latest Developments in Adapting Deep Learning for Assessing TAVR Procedures and Outcomes
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2023 , Article)
Aortic valve defects are among the most prevalent clinical conditions. A severely damaged
or non-functioning aortic valve is commonly replaced with a bioprosthetic heart valve (BHV) via the
transcatheter aortic valve ...
Computational Analysis of Wall Shear Stress Patterns on Calcified and Bicuspid Aortic Valves : Focus on Radial and Coaptation Patterns
(
MDPI
, 2021 , Article)
Calcification and bicuspid valve formation are important aortic valve disorders that disturb the hemodynamics and the valve function. The detailed analysis of aortic valve hemodynamics would lead to a better understanding ...
In vivo testing of novel nitric oxide-releasing nanoparticles for alleviating heart failure using the zebrafish embryo model
(
Elsevier
, 2024 , Article)
Heart failure (HF) is a multifactorial, heterogeneous systemic disease that is considered one of the leading causes of death and morbidity worldwide. It is well-known that endothelial dysfunction (ED) plays an important ...
Deep Learning Technique for Congenital Heart Disease Detection Using Stacking-Based CNN-LSTM Models from Fetal Echocardiogram: A Pilot Study
(
IEEE
, 2023 , Article)
Congenital heart defects (CHDs) are a leading cause of death in infants under 1 year of age. Prenatal intervention can reduce the risk of postnatal serious CHD patients, but current diagnosis is based on qualitative criteria, ...
Trilayer composite scaffold for urethral reconstruction: in vitro evaluation of mechanical, biological, and angiogenic properties
(
IOP Publishing
, 2024 , Article)
Regeneration of damaged urethral tissue remains a major challenge in the field of lower urinary tract reconstruction. To address this issue, various synthetic and natural biodegradable biomaterials are currently being ...