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Now showing items 11-20 of 20
Glycine and Folate Ameliorate Models of Congenital Sideroblastic Anemia
(
Public Library of Science (USA)
, 2016 , Article)
Sideroblastic anemias are acquired or inherited anemias that result in a decreased ability to
synthesize hemoglobin in red blood cells and result in the presence of iron deposits in the
mitochondria of red blood cell ...
Human microbiome and its association with health and diseases
(
Wiley
, 2016 , Article)
Human microbiota are distinct communities of microorganisms that resides at different body
niches. Exploration of the human microbiome has become a reality due to the availability of
powerful metagenomics and metatranscriptomic ...
Preparation, characterization, and in ovo vaccination of dextran-spermine nanoparticle DNA vaccine coexpressing the fusion and hemagglutinin genes against Newcastle disease
(
Dove Press
, 2016 , Article)
Plasmid DNA (pDNA)-based vaccines have emerged as effective subunit vaccines against viral and bacterial pathogens. In this study, a DNA vaccine, namely plasmid internal ribosome entry site-HN/F, was applied in ovo against ...
The Role of Cardiac Myosin Binding Protein C3 in Hypertrophic Cardiomyopathy- Progress and Novel Therapeutic Opportunities
(
Wiley
, 2016 , Article)
Hypertrophic cardiomyopathy (HCM) is a common autosomal dominant genetic cardiovascular disorder marked by genetic and phenotypic heterogeneity. Mutations in the gene encodes the cardiac myosin-binding protein C, cMYBPC3 ...
Reconstituted B cell receptor signaling reveals carbohydrate-dependent mode of activation
(
Nature Publishing Group
, 2016 , Article)
Activation of immune cells (but not B cells) with lectins is widely known. We used the structurally defined interaction between influenza hemagglutinin (HA) and its cell surface receptor sialic acid (SA) to identify a B ...
Impact of single-walled carbon nanotubes on the embryo: a brief review
(
Dove Press
, 2016 , Article)
Carbon nanotubes (CNTs) are considered one of the most interesting materials in the 21st century due to their unique physiochemical characteristics and applicability to various industrial products and medical applications. ...
Effectiveness of antipseudomonal antibiotics and mechanisms of multidrug resistance in Pseudomonas aeruginosa
(
Polish Society of Microbiologists
, 2016 , Article)
Pseudomonas aeruginosa is a leading human pathogen that causes serious infections at various tissues and organs leading to life threatening health problems and possible deadly outcomes. Resistance patterns vary widely ...
The frequency of polycystic ovary syndrome in young reproductive females in Qatar
(
Dove Medical Press
, 2016 , Article)
This was a prospective cross-sectional study in which 126 female students between the ages of 18 and 30 years were evaluated for the frequency of polycystic ovary syndrome (PCOS) through clinical interview, questionnaire, ...
Platelets as a Possible Reservoir of HCV And Predictor of Response to Treatment
(
SciTechnol
, 2016 , Article)
In the era of new Hepatitis C Virus (HCV) therapy, and the detection of
extrahepatic HCV reservoirs such as peripheral blood mononuclear
cells and platelets, it is important to understand the factors underlying
resistance ...
Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA)
(
BioMed Central
, 2016 , Article)
Intra-abdominal infections (IAI) are an important cause of morbidity and are frequently associated with poor prognosis, particularly in high-risk patients. The cornerstones in the management of complicated IAIs are timely ...