Search
Now showing items 1-7 of 7
Heart Function and Hemodynamics Analysis for Zebrafish Embryos
(
Wiley
, 2017 , Article)
The zebrafish has emerged to become a powerful vertebrate animal model for cardiovascular research in recent years. Its advantages include easy genetic manipulation, transparency, small size, low cost, and the ability to ...
Mechanosensitive Pathways in Heart Development: Findings from Chick Embryo Studies.
(
MDPI
, 2021 , Article)
The heart is the first organ that starts to function in a developing embryo. It continues to undergo dramatic morphological changes while pumping blood to the rest of the body. Genetic regulation of heart development is ...
Using Zebrafish for Investigating the Molecular Mechanisms of Drug-Induced Cardiotoxicity
(
Hindawi Publishing Corporation
, 2018 , Article)
Over the last decade, the zebrafish (Danio rerio) has emerged as amodel organismfor cardiovascular research.Zebrafish have several advantages over mammalian models. For instance, the experimental cost of using zebrafish ...
Fluid Flow Characteristics of Healthy and Calcified Aortic Valves Using Three-Dimensional Lagrangian Coherent Structures Analysis
(
MDPI
, 2021 , Article)
Aortic valve calcification is an important cardiovascular disorder that deteriorates the accurate functioning of the valve leaflets. The increasing stiffness due to the calcification prevents the complete closure of the ...
Numerical Investigation of the Fetal Left Heart Hemodynamics During Gestational Stages
(
Frontiers Media
, 2021 , Article)
Flow-driven hemodynamic forces on the cardiac tissues have critical importance, and have a significant role in the proper development of the heart. These mechanobiological mechanisms govern the cellular responses for the ...
Blood Flow Disturbance and Morphological Alterations Following the Right Atrial Ligation in the Chick Embryo.
(
Frontiers Media
, 2022 , Article)
Collectively known as congenital heart defects (CHDs), cardiac abnormalities at birth are the most common forms of neonatal defects. Being principally responsible for the heart's pumping power, ventricles are particularly ...
Computational Analysis of Wall Shear Stress Patterns on Calcified and Bicuspid Aortic Valves : Focus on Radial and Coaptation Patterns
(
MDPI
, 2021 , Article)
Calcification and bicuspid valve formation are important aortic valve disorders that disturb the hemodynamics and the valve function. The detailed analysis of aortic valve hemodynamics would lead to a better understanding ...