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Quantification of the growth suppression of HER2+ breast cancer colonies under the effect of trastuzumab and PD-1/PD-L1 inhibitor.

Padmanabhan, Regina; Kheraldine, Hadeel; Gupta, Ishita; Meskin, Nader; Hamad, Anas; ... more authors ... less authors ( Frontiers Media , 2022 , Article)

Immune checkpoint blockade (ICB)-based therapy is revolutionizing cancer treatment by fostering successful immune surveillance and effector cell responses against various types of cancers. However, patients with HER2+ ...

A comprehensive review summarizing the recent biomedical applications of functionalized carbon nanofibers

Abdo, Ghada G.; Zagho, Moustafa M.; Al Moustafa, Ala-Eddin; Khalil, Ashraf; Elzatahry, Ahmed A. ( John Wiley and Sons Inc , 2021 , Article)

Since the discovery and fabrication of carbon nanofibers (CNFs) over a decade ago, scientists foster to discover novel myriad potential applications for this material in both biomedicine and industry. The unique economic ...

Impact of single-walled carbon nanotubes on the embryo: a brief review

Al Moustafa, Ala-Eddin; Mfoumou, Etienne; Roman, Dacian E.; Nerguizian, Vahe; Alazzam, Anas; ... more authors ... less authors ( Dove Press , 2016 , Article)

Carbon nanotubes (CNTs) are considered one of the most interesting materials in the 21st century due to their unique physiochemical characteristics and applicability to various industrial products and medical applications. ...

E5 and E6/E7 of high-risk HPVs cooperate to enhance cancer progression through EMT initiation

Al Moustafa, Ala-Eddin ( Taylor & Francis , 2015 , Article)

It is estimated that 10–20% of human carcinogenesis is linked to virus infection including papillomaviruses (HPVs). Moreover, since metastatic cancer disease is a major cause of morbidity and mortality in cancer patients, ...

Triple Negative Breast Cancer Profile, from Gene to microRNA, in Relation to Ethnicity.

Gupta, Ishita; Sareyeldin, Rasha M.; Al-Hashimi, Israa; Al-Thawadi, Hamda A.; Al Farsi, Halema; ... more authors ... less authors ( MDPI , 2019 , Article)

Breast cancer is the most frequent cause of cancer-related deaths among women worldwide. It is classified into four major molecular subtypes. Triple-negative breast cancers (TNBCs), a subgroup of breast cancer, are defined ...