Biomedical Research Center Research: Recent submissions
Now showing items 241-260 of 708
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A highly sensitive wearable pressure sensor capsule based on PVA/Mxene composite gel
( Springer , 2022 , Article)Wearable sensors have drawn considerable interest in the recent research world. However, simultaneously realizing high sensitivity and wide detection limits under changing surrounding environment conditions remains ... -
Implications of Gut Microbiota in Epithelial–Mesenchymal Transition and Cancer Progression: A Concise Review
( MDPI , 2022 , Article Review)Advancement in the development of molecular sequencing platforms has identified infectious bacteria or viruses that trigger the dysregulation of a set of genes inducing the epithelial– mesenchymal transition (EMT) event. ... -
Effects of Previous Infection and Vaccination on Symptomatic Omicron Infections.
( Massachusetts Medical Society , 2022 , Article)The protection conferred by natural immunity, vaccination, and both against symptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection with the BA.1 or BA.2 sublineages of the omicron (B.1.1.529) ... -
Protection against the omicron variant from previous SARS-CoV-2 infection
( Massachusetts Medical Society , 2022 , Other)Natural infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) elicits strong protection against reinfection with the B.1.1.7 (alpha),1,2 B.1.351 (beta),1 and B.1.617.2 (delta)3 variants. However, the ... -
Will Host Genetics Affect the Response to SARS-CoV-2 Vaccines? Historical Precedents
( Frontiers Media , 2022 , Article Review)Recent progress in genomics and bioinformatics technologies have allowed for the emergence of immunogenomics field. This intersection of immunology and genetics has broadened our understanding of how the immune system ... -
Emerging COVID-19 variants and their impact on SARS-CoV-2 diagnosis, therapeutics and vaccines
( Taylor and Francis , 2022 , Article)The emergence of novel and evolving variants of SARS-CoV-2 has fostered the need for change in the form of newer and more adaptive diagnostic methods for the detection of SARS-CoV-2 infections. On the other hand, developing ... -
Editorial: OMICS-Based Approaches in Sports Research.
( Frontiers Media , 2022 , Other)Genomics, transcriptomics and metabolomics are increasingly generating key insights for the development of precision approaches in heath and disease. Omics technologies have unlocked the high-throughput discovery of ... -
Duration of mRNA vaccine protection against SARS-CoV-2 Omicron BA.1 and BA.2 subvariants in Qatar.
( Nature Research , 2022 , Article)SARS-CoV-2 Omicron BA.1 and BA.2 subvariants are genetically divergent. We conducted a matched, test-negative, case-control study to estimate duration of protection of the second and third/booster doses of mRNA COVID-19 ... -
Reduced Cardiotoxicity of Ponatinib-Loaded PLGA-PEG-PLGA Nanoparticles in Zebrafish Xenograft Model.
( MDPI , 2022 , Article)Tyrosine kinase inhibitors (TKIs) are the new generation of anti-cancer drugs with high potential against cancer cells' proliferation and growth. However, TKIs are associated with severe cardiotoxicity, limiting their ... -
Effects of BA.1/BA.2 subvariant, vaccination, and prior infection on infectiousness of SARS-CoV-2 omicron infections.
( Oxford University Press , 2022 , Article)Compared to BA.1, BA.2 was associated with lower RT-qPCR cycle threshold (Ct) value-3.53 fewer cycles (95% CI: 3.46-3.60), signifying higher infectiousness. This may reflect higher viral load and/or longer duration of ... -
Transmissibility and Persistence of the Plasmid-Borne Mobile Colistin Resistance Gene, mcr-1, Harbored in Poultry-Associated E. coli
( MDPI , 2022 , Article)Colistin, a last-resort antibiotic, is used to treat infections caused by multi-drug-resistant Gram-negative bacteria. Colistin resistance can emerge by acquiring the mobile colistin gene, mcr-1, usually plasmid borne. ... -
Retail Chicken Carcasses as a Reservoir of Multidrug-Resistant .
( Mary Ann Liebert , 2022 , Article)is a major cause of foodborne disease outbreaks worldwide, mainly through poultry. Recently, there has been an increase in multidrug-resistant (MDR) infections globally. The increased drug resistance results in increased ... -
Bacterial indoor air contaminations in hospitals in MENA region: a systematic review
( Taylor and Francis , 2022 , Article Review)Poor indoor air quality in healthcare settings has been tied with the increase in hospital-acquired infections. Thus, this systematic review was conducted to assess the levels and compositions of bacteria in indoor hospital ... -
Variations in respiratory syncytial virus activity following the relaxation of COVID-19 restrictions in Qatar.
( Oxford University Press , 2022 , Article)Despite the relaxation of COVID-19 restrictions in Qatar in October-December 2020, the detection of RSV was reduced ∼25-fold compared with 2019. This dramatic decrease during the typical RSV season could be related to ... -
The Effects of Class IV Hemorrhagic Hypotensive Shock and Its Resuscitation with Fluids and Adjuvant Vasopressors or Cellular Energy Replenishment on the Splanchnic Microcirculation
( Hamad bin Khalifa University Press (HBKU Press) , 2016 , Conference Paper)Traumatic exsanguination leading to class IV hemorrhagic shock as defined by the Committee on Trauma of the American College of Surgeons requires aggressive resuscitation with crystalloids and packed cells together with ... -
A comprehensive review summarizing the recent biomedical applications of functionalized carbon nanofibers
( John Wiley and Sons Inc , 2021 , Article)Since the discovery and fabrication of carbon nanofibers (CNFs) over a decade ago, scientists foster to discover novel myriad potential applications for this material in both biomedicine and industry. The unique economic ... -
Activation and Contraction of Human “Vascular” Smooth Muscle Cells Grown From Circulating Blood Progenitors
( Frontiers Media , 2021 , Article)Blood outgrowth smooth muscle cells (BO-SMCs) offer the means to study vascular cells without the requirement for surgery providing opportunities for drug discovery, tissue engineering, and personalized medicine. However, ... -
Solar cultivation of microalgae in a desert environment for the development of techno-functional feed ingredients for aquaculture in Qatar
( Elsevier , 2022 , Article)The demand for aquaculture feed will increase in the coming years in order to ensure food security for a growing global population. Microalgae represent a potential fish-feed ingredient; however, the feasibility of their ... -
Soluble ACE2 and angiotensin II levels are modulated in hypertensive COVID-19 patients treated with different antihypertension drugs.
( Taylor and Francis , 2022 , Article)This study examines the effect of antihypertensive drugs on ACE2 and Angiotensin II levels in hypertensive COVID-19 patients. Hypertension is a common comorbidity among severe COVID-19 patients. ACE2 expression can be ... -
Assessment of the Neutralizing Antibody Response of BNT162b2 and mRNA-1273 SARS-CoV-2 Vaccines in Naïve and Previously Infected Individuals: A Comparative Study
( MDPI , 2022 , Report)The currently authorized mRNA COVID-19 vaccines, Pfizer-BNT162b2 and Moderna-mRNA-1273, offer great promise for reducing the spread of the COVID-19 by generating protective immunity against SARS-CoV-2. Recently, it was ...