Biomedical Research Center Research: Recent submissions
Now showing items 661-680 of 734
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Genetically unmatched human iPSC and ESC exhibit equivalent gene expression and neuronal differentiation potential.
( Nature Publishing Group , 2017 , Article)The potential uniformity between differentiation and therapeutic potential of human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs) remains debatable. We studied the gene expression profiles, ... -
Sarcoptes-World Molecular Network (Sarcoptes-WMN): integrating research on scabies.
( Elsevier , 2011 , Article)Parasites threaten human and animal health globally. It is estimated that more than 60% of people on planet Earth carry at least one parasite, many of them several different species. Unfortunately, parasite studies suffer ... -
Antibiotic Resistance Profile of Commensal Escherichia coli Isolated from Broiler Chickens in Qatar.
( International Association for Food Protection , 2018 , Article)Antibiotic resistance (AR) is a growing public health concern worldwide, and it is a top health challenge in the 21st century. AR among Enterobacteriaceae is rapidly increasing, especially in third-generation cephalosporins ... -
A TaqMan real-time PCR-based assay for the identification of Fasciola spp.
( Elsevier , 2011 , Article)Real time quantitative PCR (qPCR) is one of the key technologies of the post-genome era, with clear advantages compared to normal end-point PCR. In this paper, we report the first qPCR-based assay for the identification ... -
Molecular identification and characterization of Cryptosporidium spp. among pediatric and food-handlers subjects in Qatar
( Frontiers Media , 2017 , Article)World Health Organization (WHO) has identified Cryptosporidium spp. as globally the most common diarrhea-causing protozoan. Its transmission occurs mainly through ingestion of water or food contaminated with the feces of ... -
Host specificity of pseudomonas aeruginosa isolates from patients with cystic fibrosis and patients from different clinical backgrounds.
( European Respiratory Society: ERJ , 2014 , Article)Background: Pseudomonas aeruginosa is one of the primary pathogens being isolated more frequently in cystic fibrosis (CF) and exhibits innate resistant to a wide range of antibiotics. Purpose: To determine whether the ... -
Comparison of intestinal parasitic infection in newly arrived and resident workers in Qatar.
( BioMed Central , 2011 , Article)The rapid growth of Qatar in the last two decades has been associated with an enormous expansion of building programs in its cities and in the provision of new service industries. This in turn has attracted a large influx ... -
A fluorescence-based polymerase chain reaction-linked single-strand conformation polymorphism (F-PCR-SSCP) assay for the identification of Fasciola spp
( Springer Verlag , 2011 , Article)The present study aimed to establish a fluorescence-based polymerase chain reaction-linked single-strand conformation polymorphism (F-PCR-SSCP) assay for the identification of Fasciola spp. Based on the sequences of the ... -
Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses
( Elsevier Inc. , 2016 , Article)Antibodies capable of neutralizing divergent influenza A viruses could form the basis of a universal vaccine. Here, from subjects enrolled in an H5N1 DNA/MIV-prime-boost influenza vaccine trial, we sorted hemagglutinin ... -
Substantial toxic effect of water-pipe smoking on the early stage of embryonic development
( Oxford University Press , 2017 , Article)Water-pipe smoking (WPS) is the most widespread tobacco use in the Middle-East, and is rapidly spreading globally. Smoke from WP contains most of the compounds present in cigarette smoke, although in different proportions. ... -
Assessment of calcified aortic valve leaflet deformations and blood flow dynamics using fluid-structure interaction modeling
( Elsevier , 2017 , Article)Aortic valve diseases are among the most common cardiovascular defects. Since a non-functioning valve results in disturbed blood flow conditions, the diagnosis of such defects is based on identification of stenosis via ... -
Improving Influenza Vaccination Rate among Primary Healthcare Workers in Qatar
( MDPI , 2017 , Article)The purpose of this study was to improve influenza vaccination, and determine factors influencing vaccine declination among health care workers (HCW) in Qatar. We launched an influenza vaccination campaign to vaccinate ... -
Assessing the burden of intestinal parasites affecting newly arrived immigrants in Qatar
( BioMed Central , 2016 , Article)In the last decades, the enormous influx of immigrants to industrialized countries has led to outbreaks of parasitic diseases, with enteric infections being amongst the most frequently encountered. In its strategy to control ... -
Coproscopy and molecular screening for detection of intestinal protozoa
( BioMed Central , 2017 , Article)Intestinal parasitosis is one of several health concerns about immigrants who travel from endemic to non-endemic regions. Reliable rapid sensitive diagnostic tools, for use in non-endemic regions, are urgently required to ... -
Estimating Seroprevalence of Herpes Simplex Virus Type 1 among Different Middle East and North African Male Populations Residing in Qatar
( Wiley , 2017 , Article)HSV-1 epidemiology in the Middle East and North Africa (MENA) remains poorly understood. Our study aimed to measure HSV-1 antibody prevalence (seroprevalence) and its age-distribution among select MENA populations residing ... -
A single tube system for the detection of Mycobacterium tuberculosis DNA using gold nanoparticles based FRET assay
( Elsevier , 2017 , Article)Abstract The global combat against MTB is limited by challenges in accurate affordable detection. In this study, a rapid, affordable, single tube system for detection of unamplified MTB16s rDNA was developed. Utilizing a ... -
Cysteamine revisited: repair of arginine to cysteine mutations.
( Springer Verlag , 2017 , Article)Cysteamine is a small aminothiol endogenously derived from coenzyme A degradation. For some decades, synthetic cysteamine has been employed for the treatment of cystinosis, and new uses of the drug continue to emerge. In ... -
Colorimetric gold nanoparticles-based assay for direct detection of Clostridium difficile in clinical isolates from Qatar
( Academic Journals , 2017 , Article)Clostridium difficile infection (CDI) is a significant health problem worldwide. Control and prevention strategies of C. difficile horizontal transmission require assays with fast detection with high specificity and ... -
Seroprevalence of hepatitis E virus among blood donors in Qatar (2013-2016)
( Wiley , 2017 , Article)BACKGROUND Hepatitis E virus (HEV) is an RNA virus transmitted mainly through zoonotic transmission or fecal–oral route. More than 80% of Qatar's population are expatriates, including many coming from hyperendemic ... -
Qatar Biobank and Qatar Genome Programs Road Map
( OMICS International , 2015 , Article)Qatar Biobank “QBB” is a large-scale, long term medical research initiative for the population of Qatar, which will serve as a platform and driver of biomedical research to achieve benefits for Qatar’s communities. Following ...
