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AuthorKircher, Tilo
AuthorKrug, Axel
AuthorStratmann, Mirjam
AuthorGhazi, Sayed
AuthorSchales, Christian
AuthorFrauenheim, Michael
AuthorTurner, Lena
AuthorFahrmann, Paul
AuthorHornig, Tobias
AuthorKatzev, Michael
AuthorGrosvald, Michael
AuthorMuller-Isberner, Rudiger
AuthorNagels, Arne
Available date2016-09-21T08:12:10Z
Publication Date2014-12
Publication NameSchizophrenia Research
Identifierhttp://dx.doi.org/10.1016/j.schres.2014.10.024
CitationKircher, T., Krug, A., Stratmann, M., Ghazi, S., Schales, C., Frauenheim, M., Turner, L., F?hrmann, P., Hornig, T., Katzev, M., Grosvald, M., Muller-Isberner, R., Nagels, A. "A rating scale for the assessment of objective and subjective formal thought and language disorder (TALD)" (2014) Schizophrenia Research, 160 (1-3), pp. 216-221.
ISSN0920-9964
URIhttp://hdl.handle.net/10576/4730
AbstractFormal thought disorder (FTD) is a core syndrome of schizophrenia. However, patients with other diagnoses, such as mania and depression amongst others, also present with FTD. We introduce a novel, comprehensive clinical rating scale, capturing the full variety of FTD phenomenology including subjective experiences. The 30-item Thought and Language Disorder (TALD) scale is based on a detailed review of the literature, encompassing all formal thought disorder symptoms reported from the early 20th century onwards. Objectively observable symptoms as well as subjective phenomena were included. Two hundred and ten participants (146 patients ICD-10 diagnoses: depression n. = 63, schizophrenia n. = 63, mania n. = 20; 64 healthy control subjects) were interviewed and symptoms rated with the TALD, TLC, HAMD, YMRS and SAPS/SANS. A principal component analyses was performed for the TALD to differentiate sub-syndromes. The principal component analysis revealed four FTD factors; objective and subjective as well as positive and negative factor dimensions. The correlation analyses with the TLC and the SAPS/SANS FTD sub-scores demonstrated the factor validity for the objective factors. The different diagnoses showed a distinct pattern of symptom severity in each of the factors, with mania patients exhibiting the highest value in the positive, objective dimension. The scale showed good psychometric results, which makes it a practicable, nosologically-open instrument for the detailed assessment of all FTD dimensions. The results strengthen the importance of subjective symptom assessment reported by the patient.
SponsorDFG (project no. Ki 588/6-1)
Languageen
PublisherElsevier
SubjectDepression
SubjectFormal thought disorder
SubjectMania
SubjectPrincipal component analyses
SubjectSchizophrenia
TitleA rating scale for the assessment of objective and subjective formal thought and language disorder (TALD)
TypeArticle
Pagination216-221
Issue Number1--3
Volume Number160


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