تصفح College of Health Sciences حسب العنوان
السجلات المعروضة 1053 -- 1072 من 1590
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Novel Comprehensive Bioinformatics Approaches to Determine the Molecular Genetic Susceptibility Profile of Moderate and Severe Asthma.
( MDPI , 2020 , Article)Asthma is a chronic inflammatory condition linked to hyperresponsiveness in the airways. There is currently no cure available for asthma, and therapy choices are limited. Asthma is the result of the interplay between genes ... -
Novel engineered nanobodies specific for N-terminal region of alpha-synuclein recognize Lewy-body pathology and inhibit in-vitro seeded aggregation and toxicity.
( FEBS PRESS , 2022 , Article)Nanobodies (Nbs), the single-domain antigen-binding fragments of dromedary heavy-chain antibodies (HCAb), are excellent candidates as therapeutic and diagnostic tools in synucleinopathies because of their small size, ... -
A novel homozygous TPM1 mutation in familial pediatric hypertrophic cardiomyopathy and in silico screening of potential targeting drugs.
( Verduci Editore s.r.l. , 2020 , Article)Familial hypertrophic cardiomyopathy (HCM) is the most common genetic cardiac disease. While sarcomeric gene mutations explain many HCM cases, the genetic basis of about half of HCM cases remains elusive. Here we aimed to ... -
Novel immunoassay technique for rapid measurement of intracellular proteins using paramagnetic particles
( Elsevier B.V. , 2013 , Article)Magnetic immunoassays have been shown to have similar detection limits to conventional immunoassays, with the advantage of reduced total assay time. The aim of this study was to demonstrate that an integrated lysis and ... -
Novel Isosteviol Derivatives Induced Apoptosis In Human Lung Cancer
( Hamad bin Khalifa University Press (HBKU Press) , 2014 , Conference Paper)Background. Cancer metastasis is the major cause of cancer death. We previously reported novel isosteviols derivatives which induced cytotoxicity in lung cancer cells. The understanding of mechanisms which regulate lung ... -
Novel mutation in an Egyptian patient with infantile Canavan disease.
( Springer Verlag (Germany) , 2016 , Article)Canavan disease (CD) is a rare fatal childhood neurological autosomal recessive genetic disease caused by mutations in the ASPA gene, which lead to catalytic deficiency of the ASPA enzyme that catalyzes the deacetylation ... -
Novel Quinuclidinone Derivatives Induced Apoptosis in Human Breast Cancer via Targeting P53
( Elsevier , 2017 , Article)Small molecules that can target human cancers have been highly sought to increase the anticancer efficacy, the present work describes the design and synthesis of novel series of five quinuclidinone derivatives (2a-2e). ... -
Novel role of BRCA1 interacting C-terminal helicase 1 (BRIP1) in breast tumour cell invasion
( Wiley Open Access , 2020 , Article)Breast cancer (BC) is the most common malignancy and the leading cause of death in women worldwide. Only 5%-10% of mutations in BRCA genes are associated with familial breast tumours in Eastern countries, suggesting the ... -
Novel therapeutic strategies for spinal osteosarcomas
( Elsevier , 2020 , Article Review)At the dawn of the third millennium, cancer has become the bane of twenty-first century man, and remains a predominant public health burden, affecting welfare and life expectancy globally. Spinal osteogenic sarcoma, a ... -
Novel thiosemicarbazides induced apoptosis in human MCF-7 breast cancer cells via JNK signaling
( Taylor & Francis , 2015 , Article)In this study, novel thiosemicarbazides and 1,3,4-oxadiazoles were synthesized and evaluated for their anticancer effects on human MCF-7 breast cancer cell lines. Among the synthesized derivatives studied, compound ... -
Nox2 activity is required in obesity-mediated alteration of bone remodeling
( Hindawi Limited , 2018 , Article)Despite increasing evidence suggesting a role for NADPH oxidases (Nox) in bone pathophysiology, whether Nox enzymes contribute to obesity-mediated bone remodeling remains to be clearly elucidated. Nox2 is one of the ... -
Nrf-2-dependent antioxidant and anti-inflammatory effects underlie the protective effect of esculeoside A against retinal damage in streptozotocin-induced diabetic rats
( Elsevier , 2024 , Article)Esculeoside A (ESA) is a tomato-derived glycoside with antioxidant and anti-inflammatory properties. The protective effect of ESA against diabetic retinopathy is not well-investigated and was the core objective of this ... -
Nurses’ Knowledge and Attitudes about Adult Post-operative Pain Assessment and Management: A Cross-Sectional Study in Qatar
( Qatar University Press , 2021 , Poster)Background: Pain has been described by clinicians, patients, and researchers alike as a complex and challenging phenomenon. People have different experiences of pain. Nurses' negative attitudes and lack of knowledge are ... -
Nutrition and Lifestyle Factors Associated with Inflammatory Bowel Disease
( Nab'a Al-Hayat Foundation , 2021 , Article)Objective Many dietary and lifestyle factors are found to be associated with the pathogenesis of IBD. The purpose of this study is to review the dietary and lifestyle factors associated with IBD. In addition, too, this ... -
Nutrition Literacy of Middle School Students and Its Influencing Factors: A Cross-Sectional Study in Chongqing, China
( Frontiers Media , 2022 , Article)Nutrition literacy plays an important role in children's dietary habits and nutrition. This study aimed to analyse the status of nutrition literacy and its influencing factors amongst middle school students in Chongqing, ... -
Nutrition Management in COVID-19 Quarantine: Hospital-Based Study
( Cambridge University Press , 2021 , Article)Background: This hospital-based study aimed to evaluate the nutritional status and dietary habits for COVID-19 patients, the amount of nutrients provided to the patients in the hospital and to detect the predictors of ... -
Nutritional quality and health risk of pepper fruit as affected by magnesium fertilization.
( wiley , 2020 , Article)Magnesium (Mg) fertilization is a promising practice to improve vegetable yield. However, its impacts on vegetable quality and human health have not been examined. Thus, a field experiment was conducted to investigate the ... -
Nuts consumption and cognitive function
( Qatar University Press , 2021 , Poster)Background: Cognitive impairments has become a global public concern. A limited number of studies suggest a positive association between nuts intake and cognitive function. Objectives: The aim of this study is to investigate ... -
Obesity and maternal perception: a cross-sectional study of children aged 6 to 8 years in Kuwait
( World Health Organization , 2019 , Article)Background: Childhood obesity is on the increase in the Middle East. Aims: This study aimed to determine the prevalence of obesity in those aged six to eight years and to investigate maternal perception of child ... -
Obesity and maternal perception: a cross-sectional study of children aged 6 to 8 years in Kuwait.
(2019 , Article)Childhood obesity is on the increase in the Middle East. This study aimed to determine the prevalence of obesity in those aged six to eight years and to investigate maternal perception of child weight. A nation-wide study ...
