Browsing College of Health Sciences by Title
Now showing items 193-212 of 1651
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Bioinformatics classification of mutations in patients with Mucopolysaccharidosis IIIA
( Springer US , 2019 , Article)Mucopolysaccharidosis (MPS) IIIA, also known as Sanfilippo syndrome type A, is a severe, progressive disease that affects the central nervous system (CNS). MPS IIIA is inherited in an autosomal recessive manner and is ... -
Bioinformatics investigation on blood-based gene expressions of Alzheimer's disease revealed ORAI2 gene biomarker susceptibility: An explainable artificial intelligence-based approach
( Springer , 2023 , Article)The progressive, chronic nature of Alzheimer's disease (AD), a form of dementia, defaces the adulthood of elderly individuals. The pathogenesis of the condition is primarily unascertained, turning the treatment efficacy ... -
Biological and biomedical functions of Penta-O-galloyl-D-glucose and its derivatives
( Springer Nature , 2014 , Other)Penta-O-galloyl-D-glucose (PGG) is a simple hydrolysable tannin in plants. PGG exists in two anomeric forms, α-PGG and β-PGG. While β-PGG can be found in a wide variety of plants, α-PGG is rather rare in nature. Numerous ... -
Biological applications of imiquimod analogues: An update (Review)
( Spandidos Publications , 2023 , Article Review)The last decade witnessed intensive efforts in drug discovery and the emergence of thousands of molecules with potential for use as therapeutic targets. However, only a few hundred of these molecules reached the stage of ... -
Biological Performance of Primary Dental Pulp Stem Cells Treated with Gold Nanoparticles
( MDPI , 2023 , Article)Gold nanoparticles (AuNPs) are one of the most stable nanoparticles that have been prevalently used as examples for biological and biomedical applications. Herein, we evaluate the effect of AuNPs on the biological processes ... -
Biological Properties of SARS-CoV-2 Variants: Epidemiological Impact and Clinical Consequences
( MDPI , 2022 , Article Review)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a virus that belongs to the coronavirus family and is the cause of coronavirus disease 2019 (COVID-19). As of May 2022, it had caused more than 500 million ... -
Biomaterials in Traumatic Brain Injury: Perspectives and Challenges
( MDPI , 2023 , Article Review)Traumatic brain injury (TBI) is a leading cause of mortality and long-term impairment globally. TBI has a dynamic pathology, encompassing a variety of metabolic and molecular events that occur in two phases: primary and ... -
Bivalent mRNA-1273.214 vaccine effectiveness against SARS-CoV-2 omicron XBB* infections
(2023 , Article)In October of 2022, Qatar introduced COVID-19 bivalent vaccination for persons ≥ 12 years using the 50-μg mRNA-1273.214 vaccine combining SARS-CoV-2 ancestral and omicron BA.1 strains.1 We estimated this vaccine’s effectiveness ... -
Black garlic production: The influence of ageing temperature and duration on some physicochemical and antioxidant properties, and sugar content
( Wiley online library , 2023 , Article)Herein, some quality characteristics (water content, pH, antioxidant activity and sugar contents) of fresh garlic (Taşköprü, Türkiye) and black garlic, which were produced under various ageing temperatures (60 °C, 70 °C ... -
Bladder neoplasms and NF-κB: an unfathomed association.
( Taylor & Francis , 2020 , Article)Bladder cancer is the second most common genitourinary tract cancer and is often recurrent and/or chemoresistant after tumor resection. Cigarette smoking, exposure to aromatic amines, and chronic infection/inflammation are ... -
Blood Homocysteine Levels Mediate the Association Between Blood Lead Levels and Cardiovascular Mortality
( Springer Nature , 2024 , Article)Lead is a heavy, toxic metal and its exposure to humans can lead to increased risk of cardiovascular disease development and mortality. Lead exposure has been shown to induce hyperhomocysteinemia (HHCy) which may be a major ... -
The Blue Button Project: Engaging Patients in Healthcare by a Click of a Button
( American Health Information Management Association , 2015 , Article)The Blue Button project has become a way for many Americans to download their health records by just a click in any way that suits them, such as in print, on a thumb drive, or on their mobile devices and smartphones. Several ... -
BNT162b2 and mRNA-1273 COVID-19 vaccine effectiveness against the SARS-CoV-2 Delta variant in Qatar.
( Nature Researc , 2021 , Article)With the global expansion of the highly transmissible SARS-CoV-2 Delta (B.1.617.2) variant, we conducted a matched test-negative case-control study to assess the real-world effectiveness of COVID-19 messenger RNA vaccines ... -
BNT162b2 antigen dose and SARS-CoV-2 omicron infection in adolescents
( Elsevier , 2023 , Other)COVID-19 vaccine antigen dose might affect protection against SARS-CoV-2 infection,1, 2 but direct evidence to quantify this effect is absent. We conducted a matched, retrospective, cohort study using a regression ... -
Body mass index and risk of Parkinson, Alzheimer, Dementia, and Dementia mortality: a systematic review and dose-response meta-analysis of cohort studies among 5 million participants
( Taylor and Francis Ltd. , 2022 , Article Review)Objective: Inconsistent results regarding the association between the Body Mass Index (BMI) and brain disorders have been reported. We performed this study to investigate the association between BMI and risk of Parkinson, ... -
Body Shape Index Is a Stronger Predictor of Diabetes.
( MDPI , 2019 , Article)Anthropometric indicators can predict the development of diabetes among adults. Among them, a new indicator (Body Shape Index) was developed. Several cohort observational studies have demonstrated that A Body Shape Index ... -
Both Short and Long Sleep Durations Are Associated with Poor Cognition and Memory in Chinese Adults Aged 55+ Years-Results from China Health and Nutrition Survey.
( MDPI , 2022 , Article)We aimed to examine the associations between sleep duration and cognitive functions and memory in older Chinese adults attending the China Health and Nutrition Survey. A total of 7924 participants 55 years and older who ... -
Breakfast consumption habits and cognitive ability in chinese youth: A six year follow‐up longitudinal cohort study
( MDPI , 2021 , Article)This study aimed to assess the relationship between breakfast composition and long‐term regular breakfast consumption and cognitive function. Participants included 835 children from the China Jintan Cohort Study for the ... -
Breaking Barriers: The Promise and Challenges of Immune Checkpoint Inhibitors in Triple-Negative Breast Cancer
( Multidisciplinary Digital Publishing Institute (MDPI) , 2024 , Article Review)Triple-negative breast cancer (TNBC) is a highly aggressive malignancy with pronounced immunogenicity, exhibiting rapid proliferation and immune cell infiltration into the tumor microenvironment. TNBC’s heterogeneity poses ... -
“Breakthrough Therapies” for Breast Cancer Metastasis.
( OMICS International , 2015 , Article)Breast Cancer Metastasis (MBC) is an ultimate death sentence remains a challenge for clinicians worldwide.According to the Metastatic Breast Cancer (MBC) Awareness Network about 155,000 patients are living nowadays with ...