بحث بسيط
السجلات المعروضة 161 -- 170 من 258
A comparative computational approach toward pharmacological chaperones (NN-DNJ and ambroxol) on N370S and L444P mutations causing Gaucher's disease.
(
Elsevier
, 2019 , Book chapter)
Gaucher's disease (GD) is the most commonly known lysosomal disorder that occurs due to mutations in the β-glucocerebrosidase (GBA) protein. Our previous findings (Thirumal Kumar, Eldous, Mahgoub, George Priya Doss, Zayed, ...
Use of Germ-Free Animal Models in Microbiota-Related Research
(
The Korean Society for Microbiology and Biotechnology
, 2015 , Article)
The large intestine is a home for trillions of microbiota, which confer many benefits on the host, including production of vitamins, absorption of nutrients, pathogen displacement, and development of the immune system. For ...
Hypertrophic cardiomyopathy-linked variants of cardiac myosin-binding protein C3 display altered molecular properties and actin interaction
(
Portland Press Ltd
, 2018 , Article)
The most common inherited cardiac disorder, hypertrophic cardiomyopathy (HCM), is characterized by thickening of heart muscle, for which genetic mutations in cardiac myosin-binding protein C3 (c-MYBPC3) gene, is the leading ...
Implication of salt stress induces changes in pigment production, antioxidant enzyme activity, and qRT-PCR expression of genes involved in the biosynthetic pathway of Bixa orellana L.
(
Springer Verlag
, 2019 , Article)
The effect of salt stress on pigment synthesis and antioxidant enzyme activity as well as in the genes involved in the biosynthetic pathway of bixin was studied. The 14-day germinated seedlings of Bixa orellana were induced ...
Cardiac rehabilitation delivery in low/middle-income countries.
(
BMJ Publishing Group
, 2019 , Article)
Cardiac rehabilitation (CR) availability, programme characteristics and barriers are not well-known in low/middle-income countries (LMICs). In this study, they were compared with high-income countries (HICs) and by CR ...
Chitosan gold nanoparticles for detection of amplified nucleic acids isolated from sputum
(
Elsevier
, 2017 , Article)
A platform for nucleic acid detection employing chitosan and chitosan coated gold nanoparticles (AuNPs)
was developed. Mycobacterium tuberculosis (MTB) was used as a model target. MTB DNA was extracted
from sputum using ...
Burden and trend of diet-related non-communicable diseases in Australia and comparison with 34 OECD countries, 1990-2015: findings from the Global Burden of Disease Study 2015.
(
Springer Verlag
, 2018 , Article)
Diet is a major determining factor for many non-communicable chronic diseases (NCDs). However, evidence on diet-related NCD burden remains limited. We assessed the trends in diet-related NCDs in Australia from 1990 to 2015 ...
Burden of diarrhea in the eastern mediterranean region, 1990-2013: Findings from the global burden of disease study 2013
(
American Society of Tropical Medicine and Hygiene
, 2016 , Article)
Diarrheal diseases (DD) are leading causes of disease burden, death, and disability, especially in children in low-income settings. DD can also impact a child's potential livelihood through stunted physical growth, cognitive ...
In vitro and in vivo inhibition of aldose reductase and advanced glycation end products by phloretin, epigallocatechin 3-gallate and [6]-gingerol
(
Elsevier
, 2016 , Article)
Abstract Hyperglycemic stress activates polyol pathway and aldose reductase (AR) key enzyme responsible for generating secondary complications during diabetes. In this study the therapeutic potential of phloretin, ...
Nanodiagnostics for tuberculosis detection
(
Taylor & Francis
, 2017 , Article)
Introduction
Tuberculosis (TB) is a leading killer worldwide. End TB strategy aims at ending the TB epidemic by 2030. Early, accurate, and affordable diagnosis represents a cornerstone to achieve this goal. Innovative ...