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RPL13A and EEF1A1 Are Suitable Reference Genes for qPCR during Adipocyte Differentiation of Vascular Stromal Cells from Patients with Different BMI and HOMA-IR
(
Public Library of Science (PLoS)
, 2016 , Article)
Real-time or quantitative PCR (qPCR) is a useful technique that requires reliable reference genes for data normalization in gene expression analysis. Adipogenesis is among the biological processes suitable for this technique. ...
Hepatic circadian clock oscillators and nuclear receptors integrate microbiome-derived signals
(
Nature Publishing Group
, 2016 , Article)
The liver is a key organ of metabolic homeostasis with functions that oscillate in response to food intake. Although liver and gut microbiome crosstalk has been reported, microbiome-mediated effects on peripheral circadian ...
Associations of Vitamin D Receptor Polymorphisms with Coronary Artery Diseases
(2016 , Poster)
Background:
Previous studies have investigated the association of rs1544410, rs7975232 and rs731236 polymorphisms on vitamin D receptor gene and its impact on diseases such as cancer, diabetes and hypertension in different ...
Metabolic shift toward oxidative phosphorylation in docetaxel resistant prostate cancer cells
(
Impact Journals
, 2016 , Article)
Drug resistance of cancer cells is recognized as the primary cause of failure of chemotherapeutic treatment in most human cancers. Growing evidences support the idea that deregulated cellular metabolism is linked to such ...
Helminth infections among long-term residents and settled immigrants in Qatar in the decade from 2005 to 2014: temporal trends and varying prevalence among subjects from different regional origins
(
BioMed Central
, 2016 , Article)
Background: Travel and migration from developing regions, where tropical diseases are common, to more developed
industrialised nations can contribute to the introduction and subsequent spread of infections. With its rapidly ...
New 3-Cyano-2-Substituted Pyridines Induce Apoptosis in MCF 7 Breast Cancer Cells
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2016 , Article)
The synthesis of new 3-cyano-2-substituted pyridines bearing various pharmacophores and functionalities at position 2 is described. The synthesized compounds were evaluated for their in vitro anti-cancer activities on five ...
Inflammogenesis of Secondary Spinal Cord Injury
(
Frontiers Media
, 2016 , Article)
Spinal cord injury (SCI) and spinal infarction lead to neurological complications and eventually to paraplegia or quadriplegia. These extremely debilitating conditions are major contributors to morbidity. Our understanding ...
Osteoporosis in patients with stroke: A cross-sectional study
(
Medknow Publications
, 2016 , Article)
Stroke-related impairments and inactivity contribute to the accelerated development of bone mass removal. However, the extent of decrease in bone mineral density (BMD) after stroke and all factors that influence such rapid ...
Identification of the Main Intermediate Precursor of l-Ergothioneine Biosynthesis in Human Biological Specimens
(
MDPI AG
, 2016 , Article)
A capillary electrophoresis coupled to tandem mass spectrometry (CE–MS/MS) has been used to make a qualitative determination of hercynine—the main precursor of l-ergothioneine biosynthesis—in some key human biological ...
Bidirectional communication between the Aryl hydrocarbon Receptor (AhR) and the microbiome tunes host metabolism
(
Nature Publishing Group in partnership with Nanyang Technological University
, 2016 , Article)
The ligand-induced transcription factor, aryl hydrocarbon receptor (AhR) is known for its capacity to tune adaptive immunity and xenobiotic metabolism-biological properties subject to regulation by the indigenous microbiome. ...