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Now showing items 121-130 of 147
Does the Mediterranean Diet Have Any Effect on Lipid Profile, Central Obesity and Liver Enzymes in Non-Alcoholic Fatty Liver Disease (NAFLD) Subjects? A Systematic Review and Meta-Analysis of Randomized Control Trials
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2023 , Article Review)
The effectiveness of the Mediterranean diet (MD) in non-alcoholic fatty liver disease (NAFLD) subjects has been evaluated in several randomized controlled trials (RCTs). This systematic review and meta-analysis aimed to ...
Breaking Barriers: The Promise and Challenges of Immune Checkpoint Inhibitors in Triple-Negative Breast Cancer
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2024 , Article Review)
Triple-negative breast cancer (TNBC) is a highly aggressive malignancy with pronounced immunogenicity, exhibiting rapid proliferation and immune cell infiltration into the tumor microenvironment. TNBC’s heterogeneity poses ...
Organoboronic acids/esters as effective drug and prodrug candidates in cancer treatments: challenge and hope
(
Taylor and Francis Ltd.
, 2023 , Article Review)
Boronic acids/esters have recently emerged in the field of medicinal and pharmaceutical research due to their exceptional oxophilicity, low toxicity, and unique structure. They are known as potent enzyme inhibitors, cancer ...
Epidemiology of herpes simplex virus type 1 in Canada: systematic review, meta-analyses, and meta-regressions
(
Frontiers Media SA
, 2023 , Article Review)
Background: The objective of this study was to characterize herpes simplex virus type 1 (HSV-1) epidemiology in Canada.
Methods: HSV-1 publications as recent as December 6, 2021 were systematically reviewed, synthesized, ...
Association between metabolically healthy obesity and metastasis in lung cancer patients – a systematic review and meta-analysis
(
Frontiers Media
, 2023 , Article Review)
Background: Many clinical trials have looked at the relationship between obesity and lung cancer (LC), however, there is scarcity of literature specifically addressing the association between metabolically healthy obesity ...
Current Technologies and Future Perspectives in Immunotherapy towards a Clinical Oncology Approach
(
MDPI
, 2024 , Article Review)
Immunotherapy is now established as a potent therapeutic paradigm engendering antitumor immune response against a wide range of malignancies and other diseases by modulating the immune system either through the stimulation ...
Therapeutic and diagnostic applications of exosomal circRNAs in breast cancer
(
Institute for Ionics
, 2023 , Article Review)
Circular RNAs (circRNAs) are regulatory elements that are involved in orchestrating gene expression and protein functions and are implicated in various biological processes including cancer. Notably, breast cancer has a ...
Disturbed hemodynamics and oxidative stress interaction in endothelial dysfunction and AAA progression: Focus on Nrf2 pathway
(
Elsevier
, 2023 , Article Review)
Hemodynamic shear stress is one of the major factors that are involved in the pathogenesis of many cardiovascular diseases including atherosclerosis and abdominal aortic aneurysm (AAA), through its modulatory effect on the ...
Metabolomics Approaches for the Diagnosis, Treatment, and Better Disease Management of Viral Infections
(
MDPI
, 2023 , Article Review)
Metabolomics is an analytical approach that involves profiling and comparing the metabolites present in biological samples. This scoping review article offers an overview of current metabolomics approaches and their ...
Using artificial intelligence to improve body iron quantification: A scoping review
(
Elsevier
, 2023 , Article Review)
This scoping review explores the potential of artificial intelligence (AI) in enhancing the screening, diagnosis, and monitoring of disorders related to body iron levels. A systematic search was performed to identify studies ...