Browsing Biomedical Sciences by Author "Qoronfleh, M. Walid"

Now showing items 1-4 of 4

    • Aberrant DNA methylation of PTPRG as one possible mechanism of its under-expression in CML patients in the State of Qatar 

      Ismail, Mohamed A; Samara, Muthanna; Al Sayab, Ali; Alsharshani, Mohamed; Yassin, Mohamed A; ... more authors ( Wiley Open Access , 2020 , Article)
      Several studies showed that aberrant DNA methylation is involved in leukemia and cancer pathogenesis. Protein tyrosine phosphatase receptor gamma (PTPRG) expression is a natural inhibitory mechanism that is downregulated ...

    • Association of single nucleotide polymorphisms with dyslipidemia and risk of metabolic disorders in the State of Qatar 

      Al-Sharshani, Dalal; Velayutham, Dinesh; Samara, Muthanna; Gazal, Reham; Al Haj Zen, Ayman; ... more authors ( Wiley-Blackwell , 2023 , Article)
      Background: Dyslipidemia is recognized as one of the risk factors of cardiovascular diseases (CVDs), type 2 diabetes mellitus (T2DM), and non-alcoholic fatty liver disease (NAFLD). Objective: The study aimed to investigate ...

    • Management of chronic myeloid leukaemia: current treatment options, challenges, and future strategies. 

      Younes, Salma; Ismail, Mohamed A; Al-Jurf, Rana; Ziyada, Ayah; Nasrallah, Gheyath K; ... more authors ( taylor and francis online , 2023 , Article)
      Small molecule therapy is a critical component of targeted anticancer treatment, with tyrosine kinase inhibitors (TKIs) being the first compounds to treat the clonal Chronic Myelogenous Leukaemia (CML) translocation t ...

    • Prevalence, predictors, and outcomes of major congenital anomalies: A population-based register study 

      Al-Dewik, Nader; Samara, Muthanna; Younes, Salma; Al-jurf, Rana; Nasrallah, Gheyath; ... more authors ( Nature Research , 2023 , Article)
      Congenital anomalies (CAs) are a leading cause of morbidity and mortality in early life. We aimed to assess the incidence, risk factors, and outcomes of major CAs in the State of Qatar. A population-based retrospective ...