تصفح Biomedical Sciences حسب المؤلف "Sharif, Elham"
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Association between Genetic Variants of GC Gene at 4q13.3 and Vitamin D Concentrations in Adult Females
sharif, Elham; Rizk, Nasser; Thakur, Hajera; Kurdi, Tasnim; Alwakeel, Mariam ( Longdom , 2019 , Article)Background: Vitamin D binding protein, encoded by the GC gene (on 4q13.3), plays an important role in transporting vitamin D. Several Genome-Wide Association Studies (GWASs) have established a significant association ... -
Associations of Vitamin D Receptor Polymorphism rs1544410 with Adiposity Phenotypes
Sharif, Elham; Swaidan, Nuha; Shurbaji, Samar; Rizk, Nasser M. ( MedCrave , 2016 , Article)Background: Vitamin D receptor (VDR) is present on adipocytes, and many studies were performed to investigate the association between polymorphisms in VDR gene with obesity. However, in the Arab Gulf populations, whereas ... -
The frequency of polycystic ovary syndrome in young reproductive females in Qatar
Sharif, Elham; Rahman, Sumaya; Zia, Yumna; Rizk, Nasser ( Dove Medical Press , 2016 , Article)This was a prospective cross-sectional study in which 126 female students between the ages of 18 and 30 years were evaluated for the frequency of polycystic ovary syndrome (PCOS) through clinical interview, questionnaire, ... -
Neutrophil Gelatinase Associated Lipocalin: Is not an Early Marker Inductor for Diabetic Nephropathy in Qatari Population
Sharif, Elham; Alwakeel, Mariam ( BJSTR , 2019 , Article)Background: The WHO Global Report on Diabetes (2016) showed that the number of diabetic patients quadrupled between 1980 and 2016, while causing the death of 1.5 million people. While the global prevalence of diabetes ... -
New markers for the detection of polycystic ovary syndrome
Sharif, Elham; Alwakeel, Mariam ( MedCrave Group , 2019 , Article)Polycystic Ovary Syndrome (PCOS) is a highly prevalent, complex genetic disorder of the endocrine system in women. Alterations that occur in women with PCOS can be due to several predisposing factors; among these contributors ... -
The role of polymorphisms in vitamin d-related genes in response to vitamin d supplementation
Tomei, Sara; Singh, Parul; Mathew, Rebecca; Mattei, Valentina; Garand, Mathieu; Alwakeel, Mariam; Sharif, Elham; Khodor, Souhaila Al... more authors ... less authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2020 , Article)Background. Vitamin D deficiency represents a major healthcare problem. Vitamin D status is influenced by genetic and environmental determinants. Several observational studies have evaluated the association of single-nucleotide ... -
TLR4 Receptor D299G/T399I Haplotype Polymorphism Is Associated with Insulin Resistance in Obese Female Subjects
Sharif, Elham; Al-Wakeel, Mariam; Mohamed, Afnan; kerkadi, Abdelhamid; Rizk, Nasser M (2020 , Article)Background: Activation of Toll-like-receptor 4 (TLR4) causes chronic inflammation that can result in obesity and metabolic syndrome (MeS). Aim: This study aimed to investigate the role of TLR4 polymorphisms of TLR4D299G/T399I, ...