تصفح Biomedical Sciences حسب المؤلف "Toft, E."
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Hypertrophic cardiomyopathy-linked variants of cardiac myosin-binding protein C3 display altered molecular properties and actin interaction
Da'as S.I.; Fakhro K.; Thanassoulas A.; Krishnamoorthy N.; Saleh A.; Calver B.L.; Safieh-Garabedian B.; Toft E.; Nounesis G.; Anthony Lai F.; Nomikos M.... more authors ... less authors ( Portland Press Ltd , 2018 , Article)The most common inherited cardiac disorder, hypertrophic cardiomyopathy (HCM), is characterized by thickening of heart muscle, for which genetic mutations in cardiac myosin-binding protein C3 (c-MYBPC3) gene, is the leading ...