Browsing Biomedical Sciences by Author "Nasser, Suzanne A."
Now showing items 1-6 of 6
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Estrogen and Bisphenol A in Hypertension
Wehbe, Zena; Nasser, Suzanne A.; El-Yazbi, Ahmed; Nasreddine, Salam; Eid, Ali H. ( Springer , 2020 , Article Review)Purpose of Review: Cardiovascular disease (CVD) is a non-subsiding disease that remains a leading cause of morbidity and mortality. CVD has been associated with endocrine disruptors, such as bisphenol A (BPA). This review ... -
Estrogen increases expression of vascular alpha 2C adrenoceptor through the cAMP/Epac/JNK/AP-1 pathway and potentiates cold-induced vasoconstriction
Fardoun, Manal M.; Issa, Khodr; Maaliki, Dina; Nasser, Suzanne A.; Baydoun, Elias; Eid, Ali H.... more authors ... less authors ( Elsevier , 2020 , Article)Cutaneous cold-induced vasoconstriction is a normal physiological reaction mediated by alpha 2C-adrenergic receptors (α2C-ARs) expressed in vascular smooth muscle cells (VSMCs). When this reaction is exaggerated, Raynaud's ... -
Inflammation and hypertension: Underlying mechanisms and emerging understandings
Aboukhater, Diana; Morad, Bassel; Nasrallah, Nadim; Nasser, Suzanne A.; Sahebkar, Amirhossein; Kobeissy, Firas; Boudaka, Ammar; Eid, Ali H.... more authors ... less authors ( wiley online library , 2023 , Article Review)Hypertension remains a major contributor to cardiovascular disease (CVD), a leading cause of global death. One of the major insults that drive increased blood pressure is inflammation. While it is the body's defensive ... -
Inflammatory basis of atherosclerosis: Modulation by sex hormones
Nasser, Suzanne A.; Afify, Elham A.; Kobeissy, Firas; Hamam, Bassam; Eid, Ali H.; El-Mas, Mahmoud M.... more authors ... less authors ( Bentham Science Publishers , 2021 , Other)Atherosclerosis-related cardiovascular diseases (CVDs) are the leading cause of death globally. Several lines of evidence are supportive of the contributory role of vascular inflammation in atherosclerosis. Di-verse immune ... -
The mitochondria: A target of polyphenols in the treatment of diabetic cardiomyopathy
Bhagani, Humna; Nasser, Suzanne A.; Dakroub, Ali; El-Yazbi, Ahmed F.; Eid, Assaad A.; Kobeissy, Firas; Pintus, Gianfranco; Eid, Ali H.... more authors ... less authors ( MDPI , 2020 , Article)Diabetic cardiomyopathy (DCM) is a constellation of symptoms consisting of ventricular dysfunction and cardiomyocyte disarray in the presence of diabetes. The exact cause of this type of cardiomyopathy is still unknown; ... -
Therapeutic potential of flavonoids in cancer: ROS-mediated mechanisms
Hasan, Slika; Mansour, Hadi; Wehbe, Nadine; Nasser, Suzanne A.; Iratni, Rabah; Nasrallah, Gheyath; Shaito, Abdullah; Ghaddar, Tarek; Kobeissy, Firas; Eid, Ali H.... more authors ... less authors ( Elsevier , 2022 , Article)Cancer is a leading cause of morbidity and mortality around the globe. Reactive oxygen species (ROS) play contradicting roles in cancer incidence and progression. Antioxidants have attracted attention as emerging therapeutic ...