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A potential link between oxidative stress and endothelial-to-mesenchymal transition in systemic sclerosis
( Frontiers Media S.A. , 2018 , Article Review)Systemic sclerosis (SSc), an autoimmune disease that is associated with a number of genetic and environmental risk factors, is characterized by progressive fibrosis and microvasculature damage in the skin, lungs, heart, ... -
Epstein-Barr virus-associated malignancies: Roles of viral oncoproteins in carcinogenesis
( Frontiers Media S.A. , 2018 , Article Review)The Epstein-Barr virus (EBV) is the first herpesvirus identified to be associated with human cancers known to infect the majority of the world population. EBV-associated malignancies are associated with a latent form of ... -
Fasting Ramadan During COVID-19 Pandemic: Immunomodulatory Effect
( Frontiers Media S.A. , 2020 , Article)As of April 24, 2020, more than 1. 6 billion Muslims observe the holy fasting month of Ramadan worldwide. The safety of fasting of healthy adult Muslims during the COVID-19 era is debatable. In this perspective, we discuss ... -
Herbal Medicine for Cardiovascular Diseases: Efficacy, Mechanisms, and Safety
( Frontiers Media S.A. , 2020 , Article)Cardiovascular diseases (CVDs) are a significant health burden with an ever-increasing prevalence. They remain the leading causes of morbidity and mortality worldwide. The use of medicinal herbs continues to be an ... -
Identification of Prognostic Metabolomic Biomarkers at the Interface of Mortality and Morbidity in Pre-Existing TB Cases Infected With SARS-CoV-2
( Frontiers Media S.A. , 2022 , Article)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection currently remains one of the biggest global challenges that can lead to acute respiratory distress syndrome (CARDS) in severe cases. In line with this, ... -
Molecular analysis of the enteric protozoa associated with acute diarrhea in hospitalized children
( Frontiers Media S.A. , 2017 , Article)Pediatric diarrhea is a common cause of death among children under 5 years of age. In the current study, we investigated the frequency of intestinal parasites among 580 pediatric patients with chronic diarrhea. Parasitic ... -
Postprandial insulin and triglyceride concentrations are suppressed in response to breaking up prolonged sitting in Qatari females
( Frontiers Media S.A. , 2019 , Article)Background: Cultural, environmental and logistical factors challenge the Qatari population, particularly females, to engage in physical activity, and there is a high prevalence of diabetes in this population. Sedentary ... -
Sex distinctive patterns in the association between serum bicarbonate and uric acid levels among healthy adults. Qatar biobank data
( Frontiers Media S.A. , 2023 , Article)Background: Uric acid is the final product of purine metabolism and is a potent plasma antioxidant but with pro-inflammatory effects. At high levels, it may increase the risk of developing multiple chronic diseases, such ...