Browsing Biomedical Sciences by Subject "nanoparticle"

Now showing items 1-4 of 4

    • Neutralization of MERS coronavirus through a scalable nanoparticle vaccine 

      Mohsen, Mona O; Rothen, Dominik; Balke, Ina; Martina, Byron; Zeltina, Vilija; ... more authors ( Springer Nature , 2021 , Article)
      MERS-CoV continues to cause human outbreaks, so far in 27 countries worldwide following the first registered epidemic in Saudi Arabia in 2012. In this study, we produced a nanovaccine based on virus-like particles (VLPs). ...

    • Reduced Cardiotoxicity of Ponatinib-Loaded PLGA-PEG-PLGA Nanoparticles in Zebrafish Xenograft Model. 

      Al-Thani, Hissa F; Shurbaji, Samar; Zakaria, Zain Zaki; Hasan, Maram H; Goracinova, Katerina; ... more authors ( MDPI , 2022 , Article)
      Tyrosine kinase inhibitors (TKIs) are the new generation of anti-cancer drugs with high potential against cancer cells' proliferation and growth. However, TKIs are associated with severe cardiotoxicity, limiting their ...

    • Thymoquinone, as a Novel Therapeutic Candidate of Cancers 

      Almajali, Belal; Nagi, Hamid Ali; Taib, Wan Rohani Wan; Ismail, Imilia Ismail; Johan, Muhammad Farid; ... more authors ( MDPI , 2021 , Article)
      To date, natural products are widely used as pharmaceutical agents for many human diseases and cancers. One of the most popular natural products that have been studied for anticancer properties is thymoquinone (TQ). As ...

    • Zebrafish as a Model for Anticancer Nanomedicine Studies. 

      Al-Thani, Hissa F; Shurbaji, Samar; Yalcin, Huseyin C ( MDPI , 2021 , Article Review)
      Nanomedicine is a new approach to fight against cancer by the development of anticancer nanoparticles (NPs) that are of high sensitivity, specificity, and targeting ability to detect cancer cells, such as the ability of ...