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Performance evaluation of five commercial assays in assessing seroprevalence of HEV antibodies among blood donors
(
Microbiology Society
, 2018 , Article)
Although hepatitis E virus (HEV) is mainly transmitted via the faecal-oral route, the rate of HEV transmission via blood donation is on the rise. However, the seroprevalence of HEV among blood donors is not well established ...
Novel Isosteviol Derivatives Induced Apoptosis In Human Lung Cancer
(
Hamad bin Khalifa University Press (HBKU Press)
, 2014 , Conference Paper)
Background. Cancer metastasis is the major cause of cancer death. We previously reported novel isosteviols derivatives which induced cytotoxicity in lung cancer cells. The understanding of mechanisms which regulate lung ...
Lipidomics for the Prediction of the Unstable Coronary Plaque
(
Hamad bin Khalifa University Press (HBKU Press)
, 2016 , Conference Paper)
Plaques that build up in the lining of the coronary arteries are made up of lipids, inflammatory cells, smooth muscle cells and connective tissue. Thormbosis of a not necessarily occlusive but unstable plaque most often ...
Prevalence of Virulence/Stress Genes in Campylobacter Jejuni from Chicken Meat Sold in Qatari Retail Outlets
(
Hamad bin Khalifa University Press (HBKU Press)
, 2016 , Conference Paper)
Chicken meat from the shelves of supermarkets in Qatar was tested for the presence of Camplobacter spp., and the presence of five virulence genes (htrB, cdtB, clpB, cadF and ciaB) was assessed in isolates. Forty eight ...
Frequency of Clinically Important RH and Kell Blood Group Antigens Among Blood Donors in Qatar
(
Hamad bin Khalifa University Press (HBKU Press)
, 2016 , Conference Paper)
Background
Very limited information is available about the prevalence of blood groups among Qatari population and residents. The information about frequencies of different blood group antigens is important to manage, ...
Helminth Infections Among Long-Term-Residents and Settled Immigrants in Qatar in the Decade from 2005 to 2014: Temporal Trends and Varying Prevalence Among Subjects from Different Regional Origins
(
Hamad bin Khalifa University Press (HBKU Press)
, 2016 , Conference Paper)
We analysed the prevalence of helminth infection in a dataset of 31,008 records of subjects referred for stool examination at the Hamad Medical Corporation over the course of a decade (2005 to 2014, inclusive). Overall ...
Durable immunity to oncogenic human papillomaviruses elicited by adjuvanted recombinant Adeno-associated virus-like particle immunogen displaying L2 17-36 epitopes
(
Elsevier
, 2015 , Article)
Vaccination with the minor capsid protein L2, notably the 17–36 neutralizing epitope, induces broadly protective antibodies, although the neutralizing titers attained in serum are substantially lower than for the licensed ...
Genotype-phenotype correlation in patients with isovaleric acidaemia: comparative structural modelling and computational analysis of novel variants.
(
Oxford University Press (OUP)
, 2017 , Article)
Isovaleric acidaemia (IVA) is an autosomal recessive inborn error of leucine metabolism. It is caused by a deficiency in the mitochondrial isovaleryl-CoA dehydrogenase (IVD) enzyme. In this study, we investigated eight ...
Nox2 activity is required in obesity-mediated alteration of bone remodeling
(
Hindawi Limited
, 2018 , Article)
Despite increasing evidence suggesting a role for NADPH oxidases (Nox) in bone pathophysiology, whether Nox enzymes contribute to obesity-mediated bone remodeling remains to be clearly elucidated. Nox2 is one of the ...
Cysteamine revisited: repair of arginine to cysteine mutations.
(
Springer Verlag
, 2017 , Article)
Cysteamine is a small aminothiol endogenously derived from coenzyme A degradation. For some decades, synthetic cysteamine has been employed for the treatment of cystinosis, and new uses of the drug continue to emerge. In ...