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Epstein–Barr Virus Epidemiology, Serology, and Genetic Variability of LMP-1 Oncogene Among Healthy Population: An Update
(
Frontiers Medi
, 2018 , Article Review)
The Epstein–Barr virus (EBV) is a DNA lymphotropic herpesvirus and the causative agent
of infectious mononucleosis. EBV is highly prevalent since it affects more than 90% of
individuals worldwide and has been linked to ...
The frequency of polycystic ovary syndrome in young reproductive females in Qatar
(
Dove Medical Press
, 2016 , Article)
This was a prospective cross-sectional study in which 126 female students between the ages of 18 and 30 years were evaluated for the frequency of polycystic ovary syndrome (PCOS) through clinical interview, questionnaire, ...
Platelets as a Possible Reservoir of HCV And Predictor of Response to Treatment
(
SciTechnol
, 2016 , Article)
In the era of new Hepatitis C Virus (HCV) therapy, and the detection of
extrahepatic HCV reservoirs such as peripheral blood mononuclear
cells and platelets, it is important to understand the factors underlying
resistance ...
Human c-MYBPC3 RNA Targeted Therapy, Reversal of Hypertrophic Cardiomyopathy in the Zebrafish Model
(
Qscience.
, 2016 , Conference Paper)
Hypertrophic cardiomyopathy (HCM) is a serious heart disease and is defined as abnormal left ventricular (LV) wall thickening with diastolic dysfunction. HCM is an autosomal dominant monogenic disease caused by a mutation ...
Reduced vasorin enhances angiotensin II signaling within the aging arterial wall
(
Impact Journals
, 2018 , Article)
The glycosylated protein vasorin physically interacts with the transforming growth factor-beta1 (TGF-β1) and functionally attenuates its fibrogenic signaling in the vascular smooth muscle cells (VSMCs) of the arterial wall. ...
Antibiotic Prescription Patterns for Upper Respiratory Tract Infections in Outpatient Qatari Population in the Private Sector
(
Elsevier
, 2016 , Article)
Background: Antibiotic are often inappropriately prescribed for upper respiratory infections (URI) in the
Western countries. Data on the proportion of inappropriate prescriptions are lacking from the Middle
East and other ...
Performance evaluation of four type-specific commercial assays for detection of herpes simplex virus type 1 antibodies in a Middle East and North Africa population.
(
Elsevier
, 2018 , Article)
The number of diagnostic assays for the detection of herpes simplex virus type 1 (HSV-1) antibodies has increased over the years. However, their performance characteristics could vary among global populations. To investigate ...
Computational insights of K1444N substitution in GAP-related domain of NF1 gene associated with neurofibromatosis type 1 disease: a molecular modeling and dynamics approach
(
Springer New York LLC
, 2018 , Article)
The NF1 gene encodes for neurofibromin protein, which is ubiquitously expressed, but most highly in the central nervous system. Non-synonymous SNPs (nsSNPs) in the NF1 gene were found to be associated with Neurofibromatosis ...
Prevalence of nephropathy in type 1 diabetes in the Arab world: A systematic review and meta-analysis
(
John Wiley and Sons Ltd
, 2018 , Article Review)
The aim of this study was to conduct a systematic review and meta-analysis and determine the prevalence of diabetic nephropathy (DN) among Arab patients with T1D. A systematic literature search was conducted using 4 different ...
Meta-analysis of the incidence of lead dislodgement with conventional and leadless pacemaker systems
(
Blackwell Publishing Inc.
, 2018 , Article Review)
Introduction
Leadless cardiac pacemaker (LCP) implantation using a transcatheter was recently developed to avoid pocket- and lead-related complications. Although a LCP has an active fixation mechanism using tines or a ...