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Now showing items 161-170 of 317
A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation causing breast cancer.
(
Elsevier
, 2019 , Article)
Breast cancer (BC) is the most commonly diagnosed cancer among females worldwide, and among the BC-associated mutations in various proteins, mutations in the RAC-alpha serine/threonine-protein kinase (AKT1) remain the most ...
Negative epidemiological association between HSV-1 and HSV-2 infections
(
Elsevier
, 2019 , Article)
Objectives: Existing evidence on an epidemiological association between herpes simplex virus (HSV) type 1 and
type 2 infections remains conflicting and inconclusive. Using a multi-national database of HSV-1/2 serologica ...
Supervised practice program guided by the Accreditation Council for Education in Nutrition and Dietetics standards improves potential employability of nutrition/dietetics graduates: perspective of employers and preceptors.
(
BMC
, 2019 , Article)
This study investigated employers' perspectives on the impact of a supervised practice program (SPP), guided by international accreditation standards on the skill development and potential employability of dietetics students. ...
MicroRNAs in Cardiac Hypertrophy
(
MDPI AG
, 2019 , Article Review)
Like other organs, the heart undergoes normal adaptive remodeling, such as cardiac hypertrophy, with age. This remodeling, however, is intensified under stress and pathological conditions. Cardiac remodeling could be ...
An extensive computational approach to analyze and characterize the functional mutations in the galactose-1-phosphate uridyl transferase (GALT) protein responsible for classical galactosemia
(
Elsevier
, 2019 , Article)
Type I galactosemia is a very rare autosomal recessive genetic metabolic disorder that occurs because of the mutations present in the galactose-1-phosphate uridyl transferase (GALT) gene, resulting in a deficiency of the ...
Conception, Implementation, and Integration of Heterogenous Information Technology Infrastructures in the Qatar Biobank
(
Mary Ann Liebert
, 2019 , Article)
The overall goal of the Qatar Biobank (QBB) is to collect, manage, and distribute high-quality human biospecimens with appropriate clinical and/or research annotation and associated phenotypic data, aiming to be an important ...
Taxane formulations: From plant to clinic
(
Springer International Publishing
, 2017 , Book chapter)
Taxanes including paclitaxel and docetaxel are highly active against many types of cancers. The main obstacle with developing delivery systems of taxanes is their poor water solubility. In this chapter, taxanes were reviewed ...
The Current Status of Cytomegalovirus (CMV) Prevalence in the MENA region: a systematic review
(
MDPI
, 2019 , Article)
Human cytomegalovirus (CMV) is a highly prevalent herpesvirus worldwide. According to
the Centers for Disease Control and Prevention (CDC) and the World Health Organization (WHO),
CMV infects people of all ages, and by ...
Performance evaluation of five ELISA kits for detecting anti-SARS-COV-2 IgG antibodies
(
Elsevier
, 2020 , Article)
ObjectivesTo evaluate and compare the performances of five commercial ELISA assays (EDI, AnshLabs, Dia.Pro, NovaTec, and Lionex) for detecting anti-SARS-CoV-2 IgG. Methods70 negative control samples (collected before the ...
Epstein-Barr virus-associated malignancies: Roles of viral oncoproteins in carcinogenesis
(
Frontiers Media S.A.
, 2018 , Article Review)
The Epstein-Barr virus (EBV) is the first herpesvirus identified to be associated with human cancers known to infect the majority of the world population. EBV-associated malignancies are associated with a latent form of ...