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Now showing items 51-60 of 66
The Therapeutic Role of Curcumin in Inflammation and Post-Surgical Outcomes
(
Taylor and Francis Ltd.
, 2023 , Article Review)
Curcumin (diferuloylmethane) is a natural polyphenolic compound that targets multiple signaling molecules and helps in supporting health benefits as it aids in the management of oxidative and inflammatory conditions. ...
Repurposing cilostazol for raynaud's phenomenon
(
Bentham Science Publishers
, 2021 , Other)
Raynaud's Phenomenon (RP) results from exaggerated cold-induced vasoconstriction. RP patients suffer from vasospastic attacks and compromised digital blood perfusion leading to a triple color change at the level the fingers. ...
Inflammatory basis of atherosclerosis: Modulation by sex hormones
(
Bentham Science Publishers
, 2021 , Other)
Atherosclerosis-related cardiovascular diseases (CVDs) are the leading cause of death globally. Several lines of evidence are supportive of the contributory role of vascular inflammation in atherosclerosis. Di-verse immune ...
A new horizon in the phosphorylated sites of AGA: the structural impact of C163S mutation in aspartylglucosaminuria through molecular dynamics simulation
(
Taylor and Francis Ltd.
, 2023 , Article)
Aspartylglucosaminuria (AGU) is a lysosomal storage disorder caused by insufficient aspartylglucosaminidase (AGA) activity leading to chronic neurodegeneration. We utilized the PhosphoSitePlus tool to identify the AGA ...
Long-term COVID-19 booster effectiveness by infection history and clinical vulnerability and immune imprinting: a retrospective population-based cohort study
(
Elsevier
, 2023 , Article)
BackgroundLong-term effectiveness of COVID-19 mRNA boosters in populations with different previous infection histories and clinical vulnerability profiles is inadequately understood. We aimed to investigate the effectiveness ...
Waning mRNA-1273 Vaccine Effectiveness against SARS-CoV-2 Infection in Qatar
(
Massachussetts Medical Society
, 2022 , Other)
In early 2021, Qatar launched a mass immunization campaign with the mRNA-1273 (Moderna)1 vaccine against coronavirus disease 2019 (Covid-19).2 We assessed the persistence of real-world vaccine effectiveness against severe ...
Intermittent fasting favorably modulates adipokines and potentially attenuates atherosclerosis
(
Elsevier Inc.
, 2023 , Article)
Adipose tissue is now recognized as an endocrine organ that secretes bioactive molecules called adipokines. These biomolecules regulate key physiological functions, including insulin sensitivity, energy metabolism, appetite ...
l-Proline-Catalyzed Three-Component Reaction of 4-Chloro-3-formylcoumarin, Sodium Sulfide, and α-Halo Ketones: A Direct Approach to Thieno[3,2- c ]coumarins
(
Georg Thieme Verlag KG
, 2023 , Other)
A new protocol for the synthesis of thieno[3,2-c]coumarins is disclosed. In this method, a 3-formyl-2-oxo-2H-chromene-4-thiolate anion is generated in situ by treatment of 4-chloro-3-formylcoumarin with sodium sulfide. ...
Identification of potential circadian genes and associated pathways in colorectal cancer progression and prognosis using microarray gene expression analysis
(
Elsevier
, 2023 , Book chapter)
Colorectal cancer (CRC) is third cancer causing death in the world. CRC is associated with disrupting the circadian rhythm (CR), closely associating the CRC progression and the dysregulation of genes involved in the ...
The impact of COVID-19 pandemic lockdown on smoking habits and lifestyle: A cross-sectional study
(
John Wiley and Sons Inc
, 2023 , Article)
Background and Aims: Throughout the COVID-19 lockdown, the resultant psychological disturbances led to more tobacco consumption and deteriorated smoking behaviors among smokers. In this study, we aimed to investigate the ...