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Amelioration of perivascular adipose inflammation reverses vascular dysfunction in a model of nonobese prediabetic metabolic challenge: potential role of antidiabetic drugs
(
Mosby Inc.
, 2019 , Article)
The onset of vascular impairment precedes that of diagnostic hyperglycemia in diabetic patients suggesting a vascular insult early in the course of metabolic dysfunction without a well-defined mechanism. Mounting evidence ...
Plasmonic MXene-based nanocomposites exhibiting photothermal therapeutic effects with lower acute toxicity than pure MXene
(
DOVE Medical Press
, 2019 , Article)
Purpose: Here, we fabricated two plasmonic 2D Ti3C2Tx-based nanocomposites (Au/MXene and Au/Fe3O4/MXene) with similarly high anti-cancer photothermal therapy (PTT) capabilities, but with less in vivo toxicity than a pure ...
Genetic epidemiology of ovarian cancer in the 22 Arab countries: A systematic review.
(
Elsevier
, 2019 , Article)
Ovarian cancer (OC) is a common disease among Arabs, with one of the highest incidences in the world. OC is underdiagnosed, underreported, and mostly reported with breast cancer. This study aimed to conduct a systematic ...
Investigation of the genetic structure of Kabyle and Chaouia Algerian populations through the polymorphism of Alu insertion markers
(
Taylor and Francis Ltd
, 2019 , Article)
Background: In Algeria, as in all North Africa, Berbers constitute the old background of the population. Today, Berber speakers account for only ∼ 25% of Algerians. This decline is the product of a complex human settlement ...
Special appreciations are given to top five peer-reviewers of journal of food quality and hazards control in 2018
(
Shahid Sadoughi University of Medical Sciences
, 2019 , Article)
[No abstract available]
The mosquito melanization response requires hierarchical activation of non-catalytic clip domain serine protease homologs.
(
Public Library of Science
, 2019 , Article)
Serine protease cascades regulate important insect immune responses namely melanization and Toll pathway activation. An important component of these cascades are clip-domain serine protease homologs (cSPHs), which are ...
Bioinformatics classification of mutations in patients with Mucopolysaccharidosis IIIA
(
Springer US
, 2019 , Article)
Mucopolysaccharidosis (MPS) IIIA, also known as Sanfilippo syndrome type A, is a severe, progressive disease that affects the central nervous system (CNS). MPS IIIA is inherited in an autosomal recessive manner and is ...
Curcumin a Colorimetric and Fluorimetric Cyanide Probe in Aqueous System and Living Cells
(
Royal Society of Chemistry
, 2019 , Article)
Curcumin, 1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-hepta-diene-3,5-dione, is a natural product obtained from the rhizome of Curcuma longa. Curcumin has been demonstrated to be a strong antioxidant with anticancer properties ...
Molecular insights of the G2019S substitution in LRRK2 kinase domain associated with Parkinson's disease: A molecular dynamics simulation approach.
(
Elsevier
, 2019 , Article)
The G2019S substitution in the Leucine-rich repeat kinase 2 (LRRK2) is significantly associated with Parkinson's disease (PD). This substitution was identified in both familial and sporadic forms of PD with a higher ...
The Implementation of an Integrated Management System at Qatar Biobank
(
Mary Ann Liebert
, 2019 , Article)
Qatar Biobank (QBB) is a platform that will make vital health research possible through its collection of samples and information on health and lifestyle from the local population of Qatar. The goal of QBB is to collect, ...