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Now showing items 11-20 of 37
Epidemiology of respiratory infections among adults in Qatar (2012-2017).
(
Public Library of Science
, 2019 , Article)
Limited data is available about the etiology of influenza like illnesses (ILIs) in Qatar. This study aimed at providing preliminary estimates of influenza and other respiratory infections circulating among adults in Qatar. ...
Genetic relationships of European, Mediterranean, and SW Asian populations using a panel of 55 AISNPs
(
Nature Publishing Group
, 2019 , Article)
The set of 55 ancestry informative SNPs (AISNPs) originally developed by the Kidd Lab has been studied on a large number of populations and continues to be applied to new population samples. The existing reference database ...
The mosquito melanization response requires hierarchical activation of non-catalytic clip domain serine protease homologs.
(
Public Library of Science
, 2019 , Article)
Serine protease cascades regulate important insect immune responses namely melanization and Toll pathway activation. An important component of these cascades are clip-domain serine protease homologs (cSPHs), which are ...
Molecular insights of the G2019S substitution in LRRK2 kinase domain associated with Parkinson's disease: A molecular dynamics simulation approach.
(
Elsevier
, 2019 , Article)
The G2019S substitution in the Leucine-rich repeat kinase 2 (LRRK2) is significantly associated with Parkinson's disease (PD). This substitution was identified in both familial and sporadic forms of PD with a higher ...
The Implementation of an Integrated Management System at Qatar Biobank
(
Mary Ann Liebert
, 2019 , Article)
Qatar Biobank (QBB) is a platform that will make vital health research possible through its collection of samples and information on health and lifestyle from the local population of Qatar. The goal of QBB is to collect, ...
Association of Urinary Vitamin D-binding Protein and Megalin as Biomarkers for Diabetic Nephropathy in Type 2 Diabetes Mellitus in Qatari Patients
(
OMICS
, 2019 , Article)
Abstract
Background: Nephropathy is a common complication of type 2 diabetes mellitus (T2DM). Previous studies
revealed that T2DM patients with nephropathy have higher concentrations of urinary Vitamin D Binding ...
Synthesis, Bioapplications, and Toxicity Evaluation of Chitosan-Based Nanoparticles.
(
MDPI
, 2019 , Article)
The development of advanced nanomaterials and technologies is essential in biomedical engineering to improve the quality of life. Chitosan-based nanomaterials are on the forefront and attract wide interest due to their ...
Integrative Bioinformatics Approaches to Map Potential Novel Genes and Pathways Involved in Ovarian Cancer.
(
Frontiers Media
, 2019 , Article)
Ovarian cancer (OC) is the seventh most commonly detected cancer among women. This study aimed to map the hub and core genes and potential pathways that might be involved in the molecular pathogenesis of OC. In the present ...
Natural History, with Clinical, Biochemical and Molecular Characterization, of Classical Homocystinuria in the Qatari Population
(
Wiley
, 2019 , Article)
Classical homocystinuria (HCU) is the most common inborn error of metabolism in Qatar, with an incidence of 1:1800, and is caused by the Qatari founder p.R336C mutation in the CBS gene. This study describes the natural ...
Sanguinarine Induces Apoptosis Pathway in Multiple Myeloma Cell Lines via Inhibition of the JaK2/STAT3 Signaling.
(
Frontiers Media
, 2019 , Article)
Sanguinarine (SNG), a benzophenanthridine alkaloid, has displayed various anticancer abilities in several vivo and studies. However, the anticancer potential of SNG is yet to be established in multiple myeloma (MM), a ...