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Rational design of a multivalent vaccine targeting arthropod-borne viruses using reverse vaccinology strategies
(
Elsevier
, 2024 , Article)
Viruses transmitted by arthropods, such as Dengue, Zika, and Chikungunya, represent substantial worldwide health threats, particularly in countries like India. The lack of approved vaccines and effective antiviral therapies ...
The impact of COVID-19 pandemic lockdown on smoking habits and lifestyle: A cross-sectional study
(
John Wiley and Sons Inc
, 2023 , Article)
Background and Aims: Throughout the COVID-19 lockdown, the resultant psychological disturbances led to more tobacco consumption and deteriorated smoking behaviors among smokers. In this study, we aimed to investigate the ...
Total and high molecular weight adiponectin in patients with coronary artery disease
(
Wolters Kluwer Health
, 2009 , Article)
BACKGROUND: Serum adiponectin inversely correlates with the extent of coronary artery disease (CAD). OBJECTIVES: To investigate the clinical significance of measuring high molecular weight (HMW) adiponectin in addition to ...
Analysis of the Qatari R336C Cystathionine β-Synthase Protein in Mice.
(
Wiley
, 2019 , Article)
Classical homocystinuria is a recessive inborn error of metabolism caused by mutations in the cystathionine beta-synthase (CBS) gene. The highest incidence of CBS deficiency in the world is found in the country of Qatar ...
Estrogen increases expression of vascular alpha 2C adrenoceptor through the cAMP/Epac/JNK/AP-1 pathway and potentiates cold-induced vasoconstriction
(
Elsevier
, 2020 , Article)
Cutaneous cold-induced vasoconstriction is a normal physiological reaction mediated by alpha 2C-adrenergic receptors (α2C-ARs) expressed in vascular smooth muscle cells (VSMCs). When this reaction is exaggerated, Raynaud's ...
The cardiovascular implication of single nucleotide polymorphisms of chromosome 9p21 locus among Arab population
(
Wolters Kluwer Health
, 2015 , Article)
Background: Based on several reports including genome-wide association studies, genetic variability has been linked with higher (nearly half) susceptibility toward coronary artery disease (CAD). We aimed to evaluate the ...
Thousands of Qatari genomes inform human migration history and improve imputation of Arab haplotypes
(
Nature Research
, 2021 , Article)
Arab populations are largely understudied, notably their genetic structure and history. Here we present an in-depth analysis of 6,218 whole genomes from Qatar, revealing extensive diversity as well as genetic ancestries ...
Antitumor Activities of the Novel Isosteviol Derivative 10C Against Liver Cancer
(
International Institute of Anticancer Research
, 2017 , Article)
Background/Aim. Hepatocellular carcinoma (HCC) is the most common type of liver cancer and the fifth most common primary malignancy with worldwide increasing incidence. The current study aims to investigate the anticancer ...
Intermittent fasting favorably modulates adipokines and potentially attenuates atherosclerosis
(
Elsevier Inc.
, 2023 , Article)
Adipose tissue is now recognized as an endocrine organ that secretes bioactive molecules called adipokines. These biomolecules regulate key physiological functions, including insulin sensitivity, energy metabolism, appetite ...
The prevalence of vitamin d deficiency among female college students at Qatar University
(
Saudi Arabian Armed Forces Hospital
, 2011 , Article)
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