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Prevalence of nephropathy in type 1 diabetes in the Arab world: A systematic review and meta-analysis
(
John Wiley and Sons Ltd
, 2018 , Article Review)
The aim of this study was to conduct a systematic review and meta-analysis and determine the prevalence of diabetic nephropathy (DN) among Arab patients with T1D. A systematic literature search was conducted using 4 different ...
Meta-analysis of the incidence of lead dislodgement with conventional and leadless pacemaker systems
(
Blackwell Publishing Inc.
, 2018 , Article Review)
Introduction
Leadless cardiac pacemaker (LCP) implantation using a transcatheter was recently developed to avoid pocket- and lead-related complications. Although a LCP has an active fixation mechanism using tines or a ...
A potential link between oxidative stress and endothelial-to-mesenchymal transition in systemic sclerosis
(
Frontiers Media S.A.
, 2018 , Article Review)
Systemic sclerosis (SSc), an autoimmune disease that is associated with a number of genetic and environmental risk factors, is characterized by progressive fibrosis and microvasculature damage in the skin, lungs, heart, ...
Drosophila as a Model Organism in Host–Pathogen Interaction Studies
(
Frontiers Media
, 2020 , Article Review)
Owing to the genetic similarities and conserved pathways between a fruit fly and mammals, the use of the Drosophila model as a platform to unveil novel mechanisms of infection and disease progression has been justified and ...
Use of Animal Models for Investigating Cardioprotective Roles of SGLT2 Inhibitors
(
Springer
, 2023 , Article Review)
Sodium-glucose co-transporter 2 (SGLT2) inhibitors represent one type of new-generation type 2 diabetes (T2DM) drug treatment. The mechanism of action of an SGLT2 inhibitor (SGLT2i) in treating T2DM depends on lowering ...
Potential Therapeutic Effects of Sodium Glucose-linked Cotransporter 2 Inhibitors in Stroke
(
Elsevier
, 2020 , Article Review)
Purpose: Stroke is the second leading cause of death and the third leading cause of disability worldwide. Diabetes mellitus and the associated hyperglycemia are important risk factors for acute ischemic stroke and are ...
The therapeutic potential of matcha tea: A critical review on human and animal studies
(
Elsevier
, 2023 , Article Review)
Matcha is a powdered form of Japanese green tea that has been gaining global popularity recently. Matcha tea has various health benefits, including an enhancing effect on cognitive function, cardio-metabolic health, and ...
Inflammation and hypertension: Underlying mechanisms and emerging understandings
(
wiley online library
, 2023 , Article Review)
Hypertension remains a major contributor to cardiovascular disease (CVD), a leading cause of global death. One of the major insults that drive increased blood pressure is inflammation. While it is the body's defensive ...
Genetic epidemiology of Woodhouse-Sakati Syndrome in the Greater Middle East region and beyond: a systematic review
(
BioMed Central Ltd
, 2023 , Article Review)
Background: Woodhouse-Sakati syndrome (WSS) is a rare, autosomal recessive genetic disorder with variable clinical manifestations mainly affecting the endocrine and nervous systems. The aim of this study was to systematically ...
An updated overview of cyanidins for chemoprevention and cancer therapy
(
Elsevier
, 2023 , Article Review)
Anthocyanins are colored polyphenolic compounds that belong to the flavonoids family and are largely present in many vegetables and fruits. They have been used in traditional medicine in many cultures for a long time. The ...