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Spectrum of mutations of familial hypercholesterolemia in the 22 Arab countries.
(
Elsevier
, 2018 , Article)
Familial hypercholesterolemia (FH) is an inherited genetic disorder of lipid metabolism characterized by a high serum LDL-cholesterol profile and xanthoma formation, and FH increases the risk of premature atherosclerosis ...
Impaired cross-talk between NO and hyperpolarization in myoendothelial feedback: a novel therapeutic target in early endothelial dysfunction of metabolic disease
(
Elsevier Ltd
, 2019 , Article Review)
Over the past three decades, our view of the endothelium rapidly evolved from a static lining of the blood vessels to a dynamic determinant and regulator of vascular tone and homeostasis. It is now widely accepted that ...
Antimicrobial Resistance of Commensal Escherichia coli Isolated from Food Animals in Qatar
(
Mary Ann Liebert
, 2020 , Article)
This study aims at evaluating the phenotypic and genotypic antimicrobial resistance (AMR) patterns of 18 clinically relevant antibiotics in food animals in Qatar. Fecal samples from camels, cattle, and pigeons (300) were ...
Therapeutic angiogenesis: From conventional approaches to recent nanotechnology-based interventions
(
Elsevier Ltd
, 2019 , Article Review)
Intentional and regulated induction of blood vessels formation which is generally referred to as therapeutic angiogenesis has a lot of potential in the management of various kinds of ischemic complications as well as in ...
Molecular Subtyping of Blastocystis from Diverse Animals in the United Arab Emirates.
(
Elsevier
, 2019 , Article)
The contribution of Blastocystis from non-human hosts to zoonotic transmission is only partly known. The objective of this study was to determine the distribution of Blastocystis genetic subtypes in different animal species ...
Durable immunity to oncogenic human papillomaviruses elicited by adjuvanted recombinant Adeno-associated virus-like particle immunogen displaying L2 17-36 epitopes
(
Elsevier
, 2015 , Article)
Vaccination with the minor capsid protein L2, notably the 17–36 neutralizing epitope, induces broadly protective antibodies, although the neutralizing titers attained in serum are substantially lower than for the licensed ...
Cysteamine revisited: repair of arginine to cysteine mutations.
(
Springer Verlag
, 2017 , Article)
Cysteamine is a small aminothiol endogenously derived from coenzyme A degradation. For some decades, synthetic cysteamine has been employed for the treatment of cystinosis, and new uses of the drug continue to emerge. In ...
Estrogen and Bisphenol A in Hypertension
(
Springer
, 2020 , Article Review)
Purpose of Review: Cardiovascular disease (CVD) is a non-subsiding disease that remains a leading cause of morbidity and mortality. CVD has been associated with endocrine disruptors, such as bisphenol A (BPA). This review ...
Computational insights of K1444N substitution in GAP-related domain of NF1 gene associated with neurofibromatosis type 1 disease: a molecular modeling and dynamics approach
(
Springer New York LLC
, 2018 , Article)
The NF1 gene encodes for neurofibromin protein, which is ubiquitously expressed, but most highly in the central nervous system. Non-synonymous SNPs (nsSNPs) in the NF1 gene were found to be associated with Neurofibromatosis ...
Prevalence of nephropathy in type 1 diabetes in the Arab world: A systematic review and meta-analysis
(
John Wiley and Sons Ltd
, 2018 , Article Review)
The aim of this study was to conduct a systematic review and meta-analysis and determine the prevalence of diabetic nephropathy (DN) among Arab patients with T1D. A systematic literature search was conducted using 4 different ...