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Vitamin B12 deficiency in diabetic patients treated with metformin: A narrative review
(2024 , Article)
Metformin is the most prescribed oral hypoglycemic drug and is considered by many health practitioners as the first-line treatment for non-insulin-dependent diabetes mellitus (T2DM). It is used either as a monotherapy or ...
Postprandial insulin and triglyceride concentrations are suppressed in response to breaking up prolonged sitting in Qatari females
(
Frontiers Media S.A.
, 2019 , Article)
Background: Cultural, environmental and logistical factors challenge the Qatari population, particularly females, to engage in physical activity, and there is a high prevalence of diabetes in this population. Sedentary ...
Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals over 10 months
(
Elsevier
, 2023 , Article)
BackgroundEvidence on the effectiveness of vaccination-induced immunity compared to SARS-CoV-2 natural immunity is warranted to inform vaccination recommendations. AimIn this study, we aimed to conduct a comparative ...
Congenital absence of appendix: a rare condition that could result in severe complications-a review of literature
(
Oxford University Press
, 2023 , Article)
Acute appendicitis is the most frequent cause of abdominal pain and acute emergency surgeries, with a mortality risk of 6-7% at its onset. Since atypical deviations in these structures are rare, they can lead to diagnosis ...
The impact of microbial composition on postprandial glycaemia and lipidaemia: A systematic review of current evidence
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2021 , Article)
Postprandial hyperglycaemia is associated with increased risk of cardiovascular disease. Recent studies highlight the role of the gut microbiome in influencing postprandial glycaemic (PPG) and lipidaemic (PPL) responses. ...
Synthesis, characterization, and antimicrobial properties of novel double layer nanocomposite electrospun fibers for wound dressing applications
(
Dove Press
, 2017 , Article)
Herein, novel hybrid nanomaterials were developed for wound dressing applications with antimicrobial properties. Electrospinning was used to fabricate a double layer nanocomposite nanofibrous mat consisting of an upper ...
Tumor reversion: a dream or a reality.
(
Pubmed
, 2021 , Article)
Reversion of tumor to a normal differentiated cell once considered a dream is now at the brink of becoming a reality. Different layers of molecules/events such as microRNAs, transcription factors, alternative RNA splicing, ...
Whole-Genome Sequencing of 100 Genomes Identifies a Distinctive Genetic Susceptibility Profile of Qatari Patients with Hypertension
(
MDPI
, 2022 , Article)
Essential hypertension (EH) is a leading risk condition for cardiovascular and renal com-plications. While multiple genes are associated with EH, little is known about its genetic etiology. Therefore, this study aimed to ...
Novel role of BRCA1 interacting C-terminal helicase 1 (BRIP1) in breast tumour cell invasion
(
Wiley Open Access
, 2020 , Article)
Breast cancer (BC) is the most common malignancy and the leading cause of death in women worldwide. Only 5%-10% of mutations in BRCA genes are associated with familial breast tumours in Eastern countries, suggesting the ...
Adiponectin Ameliorates Hyperglycemia-Induced Retinal Endothelial Dysfunction, Highlighting Pathways, Regulators, and Networks
(
dovepress
, 2022 , Article)
Background: The pathophysiology of diabetic retinopathy (DR) is multifaced. A low level of circulating adiponectin (APN) in type 2 diabetes is associated with microvasculature complications, and its role in the evolution ...