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Testosterone treatment and change of categories of the International prostate symptom score (IPSS) in hypogonadal patients: 12 years prospective controlled registry study
(
Taylor and Francis Ltd.
, 2023 , Article)
Functional hypogonadism is a condition characterized by low testosterone concentrations, occurring more commonly in men as they age. The International Prostate Symptom Score (IPSS) is used to categorize the severity of ...
Computational design of anti-cancer peptides tailored to target specific tumor markers
(
Springer Nature
, 2024 , Article)
Anti-cancer peptides (ACPs) are short peptides known for their ability to inhibit tumor cell proliferation, migration, and the formation of tumor blood vessels. In this study, we designed ACPs to target receptors often ...
Anti-cancer properties and mechanisms of action of thymoquinone, the major active ingredient of Nigella sativa
(
Taylor & Francis
, 2017 , Article)
Over the past two decades, studies have documented the wide-range anti-cancer effects of Nigella sativa, known as black seed or black cumin. Thymoquinone (TQ), its major active ingredient, has also been extensively studied ...
Reduced vasorin enhances angiotensin II signaling within the aging arterial wall
(
Impact Journals
, 2018 , Article)
The glycosylated protein vasorin physically interacts with the transforming growth factor-beta1 (TGF-β1) and functionally attenuates its fibrogenic signaling in the vascular smooth muscle cells (VSMCs) of the arterial wall. ...
Antibiotic resistance and virulence patterns of pathogenic Escherichia coli strains associated with acute gastroenteritis among children in Qatar
(
BioMed Central Ltd.
, 2020 , Article)
Background: The treatment of Enterobacteriaceae family including diarrheagenic E. coli (DEC) has been increasingly complicated due to the emergence of resistant strains. Here we report on the phenotypic resistance profiles ...
Facilitating inclusive education: Assessing faculty awareness and attitudes towards students with special educational needs at Qatar university
(
Elsevier
, 2024 , Article)
Introduction: An increasing number of students with special educational needs (SEN) are attending higher education institutions. Faculty members are key players in the implementation of inclusive policies, the success of ...
Proteomic Analysis of Prehypertensive and Hypertensive Patients: Exploring the Role of the Actin Cytoskeleton
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2024 , Article)
Hypertension is a pervasive and widespread health condition that poses a significant risk factor for cardiovascular disease, which includes conditions such as heart attack, stroke, and heart failure. Despite its widespread ...
Association between Genetic Variants of GC Gene at 4q13.3 and Vitamin D Concentrations in Adult Females
(
Longdom
, 2019 , Article)
Background: Vitamin D binding protein, encoded by the GC gene (on 4q13.3), plays an important role in
transporting vitamin D. Several Genome-Wide Association Studies (GWASs) have established a significant
association ...
Integrated structural proteomics and machine learning-guided mapping of a highly protective precision vaccine against mycoplasma pulmonis
(
Elsevier
, 2024 , Article)
Mycoplasma pulmonis (M. pulmonis) is an emerging respiratory infection commonly linked to prostate cancer, and it is classified under the group of mycoplasmas. Improved management of mycoplasma infections is essential due ...
Inhibition of cytochrome P450 epoxygenase promotes endothelium-to-mesenchymal transition and exacerbates doxorubicin-induced cardiovascular toxicity
(
Springer Nature
, 2024 , Article)
Background: Doxorubicin (DOX) is a potent chemotherapy widely used in treating various neoplastic diseases. However, the clinical use of DOX is limited due to its potential toxic effect on the cardiovascular system. Thus, ...