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Microbiota-derived acetate activates intestinal innate immunity via the Tip60 histone acetyltransferase complex
(
Elsevier
, 2021 , Article)
Microbe-derived acetate activates the Drosophila immunodeficiency (IMD) pathway in a subset of enteroendocrine cells (EECs) of the anterior midgut. In these cells, the IMD pathway co-regulates expression of antimicrobial ...
Enteric pathogens modulate metabolic homeostasis in the Drosophila melanogaster host
(
Elsevier
, 2022 , Article)
On quotidian basis, living beings work out an armistice with their microbial flora and a scuffle with invading pathogens to maintain a normal state of health. Although producing virulence factors and escaping the host's ...