Browsing Public Health by Subject "SARS-CoV-2"

Now showing items 1-17 of 17

    • Analyzing inherent biases in SARS-CoV-2 PCR and serological epidemiologic metrics 

      Makhoul, Monia; Abou-Hijleh, Farah; Seedat, Shaheen; Mumtaz, Ghina R.; Chemaitelly, Hiam; ... more authors ( springer nature , 2022 , Article)
      Background: Prospective observational data show that infected persons with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remain polymerase chain reaction (PCR) positive for a prolonged duration, and that ...

    • Association of Prior SARS-CoV-2 Infection With Risk of Breakthrough Infection Following mRNA Vaccination in Qatar. 

      Abu-Raddad, Laith J; Chemaitelly, Hiam; Ayoub, Houssein H; Yassine, Hadi M; Benslimane, Fatiha M; ... more authors ( American Medical Association , 2021 , Article)
      The effect of prior SARS-CoV-2 infection on vaccine protection remains poorly understood. To assess protection from SARS-CoV-2 breakthrough infection after mRNA vaccination among persons with vs without prior SARS-CoV-2 ...

    • BNT162b2 antigen dose and SARS-CoV-2 omicron infection in adolescents 

      Chemaitelly, Hiam; Ayoub, Houssein H.; Coyle, Peter; Tang, Patrick; Yassine, Hadi M.; ... more authors ( Elsevier , 2023 , Other)
      COVID-19 vaccine antigen dose might affect protection against SARS-CoV-2 infection,1, 2 but direct evidence to quantify this effect is absent. We conducted a matched, retrospective, cohort study using a regression ...

    • Characterizing the effective reproduction number during the COVID-19 pandemic: Insights from Qatar's experience 

      Bsat, Raghid; Chemaitelly, Hiam; Coyle, Peter; Tang, Patrick; Hasan, Mohammad R.; ... more authors ( Edinburgh University Global Health Society , 2022 , Article)
      Background The effective reproduction number, Rt, is a tool to track and understand pandemic dynamics. This investigation of Rt estimations was conducted to guide the national COVID-19 response in Qatar, from the onset of ...

    • Characterizing the effective reproduction number during the COVID-19 pandemic: Insights from Qatar’s experience 

      Bsat, Raghid; Chemaitelly, Hiam; Coyle, Peter; Tang, Patrick; Hasan, Mohammad R; ... more authors ( International Society of Global Health , 2022 , Article)
      Background: The effective reproduction number, Rt, is a tool to track and understand epidemic dynamics. This investigation of Rt estimations was conducted to guide the national COVID-19 response in Qatar, from the onset ...

    • Effectiveness of the neutralizing antibody sotrovimab among high-risk patients with mild-to-moderate SARS-CoV-2 in Qatar 

      Ahmed, Zaqout; Almaslamani, Muna A.; Chemaitelly, Hiam; Hashim, Samar A.; Ittaman, Ajithkumar; ... more authors ( Elsevier , 2022 , Article)
      ObjectivesTo estimate the real-world effectiveness of sotrovimab against severe, critical, or fatal COVID-19 in Qatar at a time in which most SARS-CoV-2 incidences occurred due to the BA.2 Omicron subvariant. MethodsWe ...

    • Estimates of global SARS-CoV-2 infection exposure, infection morbidity, and infection mortality rates in 2020 

      Houssein H., Ayoub; Mumtaz, Ghina R.; Seedat, Shaheen; Makhoul, Monia; Chemaitelly, Hiam; ... more authors ( Elsevier , 2021 , Article)
      We aimed to estimate, albeit crudely and provisionally, national, regional, and global proportions of respective populations that have been infected with SARS-CoV-2 in the first year after the introduction of this virus ...

    • Estimating protection afforded by prior infection in preventing reinfection: Applying the test-negative study design. 

      Ayoub, Houssein H; Tomy, Milan; Chemaitelly, Hiam; Altarawneh, Heba N; Coyle, Peter; ... more authors ( Oxford University Press , 2023 , Article)
      The COVID-19 pandemic has highlighted the need to use infection testing databases to rapidly estimate effectiveness of prior infection in preventing reinfection ($P{E}_S$) by novel SARS-CoV-2 variants. Mathematical modeling ...

    • Long-term COVID-19 booster effectiveness by infection history and clinical vulnerability and immune imprinting: a retrospective population-based cohort study 

      Hiam, Chemaitelly; Ayoub, Houssein H; Tang, Patrick; Coyle, Peter; Yassine, Hadi M; ... more authors ( Elsevier , 2023 , Article)
      BackgroundLong-term effectiveness of COVID-19 mRNA boosters in populations with different previous infection histories and clinical vulnerability profiles is inadequately understood. We aimed to investigate the effectiveness ...

    • Modeling the population-level impact of treatment on COVID-19 disease and SARS-CoV-2 transmission 

      Monia, Makhoul; Abu-Hijleh, Farah; Ayoub, Houssein H.; Seedat, Shaheen; Chemaitelly, Hiam; ... more authors ( Elsevier , 2022 , Article)
      Different COVID-19 treatment candidates are under development, and some are becoming available including two promising drugs from Merck and Pfizer. This study provides conceptual frameworks for the effects of three types ...

    • Platforms Exploited for SARS-CoV-2 Vaccine Development. 

      Mathew, Shilu; Faheem, Muhammed; Hassain, Neeraja A; Benslimane, Fatiha M; Thani, Asmaa A Al; ... more authors ( MDPI , 2020 , Article Review)
      The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the only zoonotic-origin coronavirus (CoV) that has reached the pandemic stage. The virus uses its spike (S) glycoprotein to attach to the host cells ...

    • Prevalence and factors associated with general anxiety symptoms severity among older adults registered with the Primary Healthcare Corporation during the COVID-19 pandemic: A cross-sectional study 

      Syed, Raana Nishat; Ziyada, Aza; Athar, Hena; Khan, Javaria; Shraim, Mujahed ( HBKU Press , 2023 , Article)
      Background: Primary care-based studies examining the prevalence of anxiety symptoms severity and associated factors among older adults during the COVID-19 pandemic are scarce. The study aims to determine the prevalence of ...

    • Prior Statins Use and Risk of Mortality and Severe Disease from COVID-19: A Systematic Review and Meta-Analysis 

      Yetmar, Zachary A; Chesdachai, Supavit; Kashour, Tarek; Riaz, Muhammad; Gerberi, Danielle J; ... more authors ( Oxford University Press , 2021 , Article)
      Background Statins up-regulate angiotensin converting enzyme-2, the receptor of SARS-CoV-2, while also exhibiting pleiotropic antiviral, antithrombotic and anti-inflammatory properties. Uncertainties exist about their ...

    • Protection of Omicron sub-lineage infection against reinfection with another Omicron sub-lineage 

      Chemaitelly, Hiam; Ayoub, Houssein H.; Coyle, Peter; Tang, Patrick; Yassine, Hadi M.; ... more authors ( Nature Research , 2022 , Article)
      There is significant genetic distance between SARS-CoV-2 Omicron (B.1.1.529) variant BA.1 and BA.2 sub-lineages. This study investigates immune protection of infection with one sub-lineage against reinfection with the other ...

    • Rates of recurrent positive SARS-CoV-2 swab results among patients attending primary care in Qatar 

      Hamed, Ehab; Sedeeq, Saad; Alnuaimi, Ahmed Sameer; Syed, Mohamed; ElHamid, Mohamed Abd; ... more authors ( Elsevier , 2021 , Article)
      We read with interest the work of COCOREC (Collaborative study COvid RECurrences) study group.1 Recurrent positive rt-PCR results for SARS-CoV-2 infection were reported from early in the epidemic.1 , 2 , 3 , 4 , ...

    • The prevalence of adaptive immunity to COVID-19 and reinfection after recovery - a comprehensive systematic review and meta-analysis of 12 011 447 individuals 

      Alshibly, Rafal; Shalaby, Rana; Musa, Omran A. H.; Hindy, George; Islam, Nazmul; ... more authors ( Qatar University Press , 2021 , Poster)
      Research purpose: The research aims to estimate the prevalence of detectable SARS-CoV-2 antibodies, T and B memory cells after recovery, to determine the prevalence of SARS-CoV-2 reinfection, and to investigate the protective ...

    • Two prolonged viremic SARS-CoV-2 infections with conserved viral genome for two months 

      Laith J., Abu-Raddad; Chemaitelly, Hiam; Malek, Joel A.; Ahmed, Ayeda A.; Mohamoud, Yasmin A.; ... more authors ( Elsevier , 2021 , Article)
      We document two cases of viremic and prolonged active infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) where the viral genome was conserved for two months, but infection was with little or ...