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INVESTIGATION OF THE HUMORAL IMMUNE RESPONSES IN SARS-COV-2 INFECTED AND VACCINATED INDIVIDUALS
(Biomedical Sciences, 06-2 , Master Thesis)
Background: Protective and lasting immunity to viral infections or vaccines are usually achieved through the combined actions of both cellular and humoral immune responses. Although there exists clear evidence supporting ...
THE ROLE OF ENTEROENDOCRINE SECRETED GUT PEPTIDE HORMONES IN MODULATING IMMUNITY AND METABOLISM IN DROSOPHILA MELANOGASTER
(Biomedical Sciences, 2021 , Master Thesis)
The intestine of all living organisms fosters an ecosystem of commensal microbiota that plays key roles in the maintenance of host health and pathology. Captivatingly, the influence of dysbiosis on the host has demonstrated ...
THE IMPACT OF HSA-MIR-146A-5P ON HUMAN RETINAL ENDOTHELIAL CELLS IN DIABETIC CONDITIONS
(Biomedical Sciences, 2021 , Master Thesis)
Background: Diabetic retinopathy (DR) is a microvascular complication of diabetes that leads to visual impairment in the adult population with effective available therapy. Micro-Ribonucleic acids (miRNAs) are small (?22 ...
GENERATION AND CHARACTERIZATION OF "OFF-THE-SHELF" CHIMERIC ANTIGEN RECEPTOR ENGINEERED T CELLS (CAR-T) TO TARGET CANCER PATIENTS WITH HEMATOLOGICAL MALIGNANCIES
(Biomedical Sciences, 2021 , Master Thesis)
Background: The usage of T cells engineered with a tumor-specific chimeric antigen receptor (CAR) for the therapeutic treatment of some types of hematological malignancies demonstrated great clinical success. However, the ...
THE ROLE OF NUTRITIONAL STATUS AS AN EPIGENETIC MODULATOR IN TYPE 1 DIABETES IN PEDIATRIC POPULATION OF QATAR
(Biomedical Sciences, 2021 , Master Thesis)
Type 1 Diabetes Mellites (T1DM), is an autoimmune disorder caused by the destruction of pancreatic b?-cells and is considered to be among the most prevalent chronic conditions in Qatar. This study aimed to identify the ...
DEVELOPMENT AND IN VIVO TESTING OF SMART NANOPARTICLES FOR ENHANCED ANTI-CANCER ACTIVITY AND REDUCED CARDIOTOXICITY ASSOCIATED WITH TYROSINE KINASE INHIBITORS
(Biomedical Sciences, 2021 , Master Thesis)
Tyrosine kinase inhibitors (TKIs) are new generation of anti-cancer drugs with very high efficiency against cancer cells. However, TKIs are associated with severe cardiotoxicity limiting their clinical benefits. One ...
NASAL EXPRESSION OF ANIOTENSIN-CONVERTING ENZYME 2 (ACE2) IN CHILDREN AND ADULTS WITH COVID-19
(Biomedical Sciences, 2021 , Master Thesis)
"Emerging evidence suggests that the lower expression of SARS-CoV-2 entry factor angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2) in the nasal epithelium of children may contribute to ...
EVALUATION OF LABORATORY CLINICAL TRAINING INTERNSHIP OF A NAACLS ACCREDITED PROGRAM IN QATAR: GRADUATES PERSPECTIVE
(Biomedical Sciences, 2021 , Master Thesis)
Background: The medical laboratory educational programs (Medical Laboratory Science and Medical Laboratory Technology) accredited by the National Accrediting Agency for Clinical Laboratory Sciences (NAACLS) provide the ...
The Association between Dietary Patterns and Hypothyroidism in Adult Population
(Biomedical Sciences, 2023 , Master Thesis)
Background: The thyroid gland produces hormones that are essential for various body functions. Hypothyroidism occurs when the thyroid gland cannot produce enough hormones. Even though several studies have found associations ...
Dietary Quality, Meal Timing and Circadian Syndrome Among Adults Attending NHANES 2005-2016
(Biomedical Sciences, 2023 , Master Thesis)
Background: Apart from diet quality, meal timing and shift work have also emerged as risk factors for cardiometabolic disease and are associated with circadian rhythm disturbances. Circadian Syndrome (CircS) is a novel ...