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GENERATION AND CHARACTERIZATION OF "OFF-THE-SHELF" CHIMERIC ANTIGEN RECEPTOR ENGINEERED T CELLS (CAR-T) TO TARGET CANCER PATIENTS WITH HEMATOLOGICAL MALIGNANCIES
(Biomedical Sciences, 2021 , Master Thesis)
Background: The usage of T cells engineered with a tumor-specific chimeric antigen receptor (CAR) for the therapeutic treatment of some types of hematological malignancies demonstrated great clinical success. However, the ...
THE ROLE OF NUTRITIONAL STATUS AS AN EPIGENETIC MODULATOR IN TYPE 1 DIABETES IN PEDIATRIC POPULATION OF QATAR
(Biomedical Sciences, 2021 , Master Thesis)
Type 1 Diabetes Mellites (T1DM), is an autoimmune disorder caused by the destruction of pancreatic b?-cells and is considered to be among the most prevalent chronic conditions in Qatar. This study aimed to identify the ...
EVALUATION OF LABORATORY CLINICAL TRAINING INTERNSHIP OF A NAACLS ACCREDITED PROGRAM IN QATAR: GRADUATES PERSPECTIVE
(Biomedical Sciences, 2021 , Master Thesis)
Background: The medical laboratory educational programs (Medical Laboratory Science and Medical Laboratory Technology) accredited by the National Accrediting Agency for Clinical Laboratory Sciences (NAACLS) provide the ...
THE ROLE OF ENTEROENDOCRINE SECRETED GUT PEPTIDE HORMONES IN MODULATING IMMUNITY AND METABOLISM IN DROSOPHILA MELANOGASTER
(Biomedical Sciences, 2021 , Master Thesis)
The intestine of all living organisms fosters an ecosystem of commensal microbiota that plays key roles in the maintenance of host health and pathology. Captivatingly, the influence of dysbiosis on the host has demonstrated ...
INVESTIGATION OF THE HUMORAL IMMUNE RESPONSES IN SARS-COV-2 INFECTED AND VACCINATED INDIVIDUALS
(Biomedical Sciences, 06-2 , Master Thesis)
Background: Protective and lasting immunity to viral infections or vaccines are usually achieved through the combined actions of both cellular and humoral immune responses. Although there exists clear evidence supporting ...
CHARACTERIZING WITHIN-HOST DIVERSITY IN SHORT-TERM AND VACCINATED COVID-19 PATIENTS
(Biomedical Sciences, 2023 , Master Thesis)
SARS-CoV-2 is the etiological agent of the ongoing COVID-19 pandemic, which has caused massive losses in human lives and strained global health resources. The ongoing vaccination campaigns in many countries have spurred ...
DIFFERENTIAL EXPRESSION OF MICRORNAS BY ANTI-OBESITY TREATMENT SULFORAPHANE IN SKELETAL MUSCLE OF DIET-INDUCED OBESITY IN MICE
(Biomedical Sciences, 2023 , Master Thesis)
Background: Skeletal muscles account for 40-60% of total body weight and are responsible for 30% of resting metabolic rate. They are essential for metabolic homeostasis in the body as they provide the leading site for ...
PROFILE OF LONG NON-CODING RNA IN RESPONSE TO SULFORAPHANE ANTI-OBESITY TREATMENT IN SKELETAL MUSCLES OF DIET INDUCED OBESITY MICE
(Biomedical Sciences, 2023 , Master Thesis)
Background: World Health Organization data reveal a rapid growth in obesity worldwide, making it a major public health concern. Obesity has been studied extensively in recent decades; however, it is still challenging due ...
Testing the Anticancer Effect of Matcha Using Zebrafish as an Animal Model
(Biomedical Sciences, 2023 , Master Thesis)
Cancer is the second leading cause of death worldwide. Triple-negative breast cancer (TNBC) patients show the poorest prognosis and survival and the highest metastasis prevalence among all breast cancer subtypes. Matcha ...
The impact of COVID-19 crisis on the testing process of the Primary Health Care Corporation (PHCC) Laboratories in state of Qatar
(Biomedical Sciences, 2023 , Master Thesis)
Introduction
The global healthcare systems have been significantly impacted by the coronavirus COVID-19 pandemic. It was a public health emergency that affects many health care services, including primary health care and ...