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ANTI-CANCER ACTIVITY OF SANGUINARINE ON HUMAN PAPILLARY THYROID CANCER CELL LINES BY TARGETING JAK/STAT3 PATHWAY
(Biomedical Sciences, 2021 , Master Thesis)
Background: Papillary thyroid carcinoma is the furthermost common type of thyroid
cancer, representing 85 % of all thyroid cancer cases. It occurs more frequently in
women and usually affects 20-55 year age group. Aim: ...
NASAL EXPRESSION OF ANIOTENSIN-CONVERTING ENZYME 2 (ACE2) IN CHILDREN AND ADULTS WITH COVID-19
(Biomedical Sciences, 2021 , Master Thesis)
"Emerging evidence suggests that the lower expression of SARS-CoV-2 entry factor angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2) in the nasal epithelium of children may contribute to ...
DEVELOPMENT AND IN VIVO TESTING OF SMART NANOPARTICLES FOR ENHANCED ANTI-CANCER ACTIVITY AND REDUCED CARDIOTOXICITY ASSOCIATED WITH TYROSINE KINASE INHIBITORS
(Biomedical Sciences, 2021 , Master Thesis)
Tyrosine kinase inhibitors (TKIs) are new generation of anti-cancer drugs with very high efficiency against cancer cells. However, TKIs are associated with severe cardiotoxicity limiting their clinical benefits. One ...
COVID-19 VACCINATION KNOWLEDGE AND HESITANCY AMONG STUDENTS AND EMPLOYEES AT QATAR UNIVERSITY; A CROSS-SECTIONAL STUDY
(Biomedical Sciences, 2021 , Professional Masters Project)
Introduction: Vaccines are the most important and cost-effective public health tools known to control and prevent many infectious diseases. However, concerns regarding the safety and the need for a vaccine and reluctance ...
BIOMEDICAL WASTE MANAGEMENT AWARENESS AMONG HEALTH SCIENCE STUDENTS AT QATAR UNIVERSITY
(Biomedical Sciences, 2021 , Professional Masters Project)
Introduction: Biomedical waste is any kind of waste that contains infectious or potentially infectious products that are generated during diagnosis, treatment, or research. At Qatar University (QU), the production of waste ...
THE IMPACT OF HSA-MIR-146A-5P ON HUMAN RETINAL ENDOTHELIAL CELLS IN DIABETIC CONDITIONS
(Biomedical Sciences, 2021 , Master Thesis)
Background: Diabetic retinopathy (DR) is a microvascular complication of diabetes that leads to visual impairment in the adult population with effective available therapy. Micro-Ribonucleic acids (miRNAs) are small (?22 ...
GENERATION AND CHARACTERIZATION OF "OFF-THE-SHELF" CHIMERIC ANTIGEN RECEPTOR ENGINEERED T CELLS (CAR-T) TO TARGET CANCER PATIENTS WITH HEMATOLOGICAL MALIGNANCIES
(Biomedical Sciences, 2021 , Master Thesis)
Background: The usage of T cells engineered with a tumor-specific chimeric antigen receptor (CAR) for the therapeutic treatment of some types of hematological malignancies demonstrated great clinical success. However, the ...
THE ROLE OF NUTRITIONAL STATUS AS AN EPIGENETIC MODULATOR IN TYPE 1 DIABETES IN PEDIATRIC POPULATION OF QATAR
(Biomedical Sciences, 2021 , Master Thesis)
Type 1 Diabetes Mellites (T1DM), is an autoimmune disorder caused by the destruction of pancreatic b?-cells and is considered to be among the most prevalent chronic conditions in Qatar. This study aimed to identify the ...
EVALUATION OF LABORATORY CLINICAL TRAINING INTERNSHIP OF A NAACLS ACCREDITED PROGRAM IN QATAR: GRADUATES PERSPECTIVE
(Biomedical Sciences, 2021 , Master Thesis)
Background: The medical laboratory educational programs (Medical Laboratory Science and Medical Laboratory Technology) accredited by the National Accrediting Agency for Clinical Laboratory Sciences (NAACLS) provide the ...
THE ROLE OF ENTEROENDOCRINE SECRETED GUT PEPTIDE HORMONES IN MODULATING IMMUNITY AND METABOLISM IN DROSOPHILA MELANOGASTER
(Biomedical Sciences, 2021 , Master Thesis)
The intestine of all living organisms fosters an ecosystem of commensal microbiota that plays key roles in the maintenance of host health and pathology. Captivatingly, the influence of dysbiosis on the host has demonstrated ...