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AuthorThalib, Lukman
AuthorFuruya-Kanamori, Luis
AuthorAlHabib, Khalid F.
AuthorAlfaleh, Hussam F.
AuthorAlShamiri, Mostafa Q.
AuthorAmin, Haitham
AuthorAl Suwaidi, Jassim
AuthorSulaiman, Kadhim
AuthorAlmahmeed, Wael
AuthorAlsheikh-Ali, Alawi A.
AuthorAl-Motarreb, Ahmed
AuthorDoi, Suhail A.R.
Available date2016-10-10T08:27:53Z
Publication Date2016-07-18
Publication NameAngiology
CitationThalib, L., Furuya-Kanamori, L., AlHabib, K. F. , Alfaleh, H. F. , AlShamiri, M. Q. , Amin, H., Al Suwaidi, J., Sulaiman, K., Almahmeed, W., Alsheikh-Ali, A. A. , Al-Motarreb, A., Doi, S. A. R.” Validation of the 6-Month GRACE Score in Predicting 1-Year Mortality of Patients With Acute Coronary Syndrome Admitted to the Arabian Gulf Hospitals”(2016). ANGIOLOGY, Vol 68, Issue 3, pp. 251 - 256
AbstractAcute coronary syndromes (ACS) are the most common cardiovascular diseases and are associated with a significant risk of mortality and morbidity. The Global Registry of Acute Coronary Events (GRACE) risk score postdischarge is a widely used ACS prediction model for risk of mortality (low, intermediate, and high); however, it has not yet been validated in patients from the Arabian Gulf. This prospective multicenter study (second Gulf Registry of Acute Coronary Events) provides detailed information of the GRACE risk score postdischarge in patients from the Arabian Gulf. Its prognostic utility was validated at 1-year follow-up in over 5000 patients with ACS from 65 hospitals in 6 Arabian Gulf countries (Bahrain, Saudi Arabia, Qatar, Oman, United Arab Emirates, and Yemen). Overall, the goodness of fit (Hosmer and Lemeshow statistic P value = .826), calibration, and discrimination (area under the receiver operating characteristic curve = 0.695; 95% confidence interval: 0.668-0.722) were good. The GRACE risk score postdischarge can be used to stratify 1 year mortality risk in the Arabian Gulf population; it does not require further calibration and has a good discriminatory ability.
SponsorGulf RACE-2 is a Gulf Heart Association (GHA) project and was financially supported by the GHA, Sanofi-Aventis, and the Deanship of Scientific Research at King Saud University, Riyadh, Saudi Arabia (Research group number: RG-1436-013). L.F.K. is funded by an Endeavour Postgraduate Scholarship (#3781_2014), an Australian National University Higher Degree Scholarship, and a Fondo para la Innovacio´n, Ciencia y Tecnologı´a Scholarship (#095-FINCyTBDE-2014).
PublisherSAGE Publications
SubjectGRACE risk score
acute coronary syndrome
TitleValidation of the 6-Month GRACE Score in Predicting 1-Year Mortality of Patients With Acute Coronary Syndrome Admitted to the Arabian Gulf Hospitals
Issue Number3
Volume Number68

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