Show simple item record

AuthorSalaheldin, Taher A.
AuthorHusseiny, Sherif M.
AuthorAl-Enizi, Abdullah M.
AuthorElzatahry, Ahmed
AuthorCowley, Alan H.
Available date2016-10-24T10:08:11Z
Publication Date2016-03-03
Publication NameInternational Journal of Molecular Scienceen_US
Identifierhttp://dx.doi.org/10.3390/ijms17030329
CitationSalaheldin, T.A.; Husseiny, S.M.; Al-Enizi, A.M.; Elzatahry, A.; Cowley, A.H. Evaluation of the Cytotoxic Behavior of Fungal Extracellular Synthesized Ag Nanoparticles Using Confocal Laser Scanning Microscope. Int. J. Mol. Sci. 2016, 17, 329.
URIhttp://hdl.handle.net/10576/4922
AbstractSilver nanoparticles have been synthesized by subjecting a reaction medium to a Fusarium oxysporum biomass at 28 °C for 96 h. The biosynthesized Ag nanoparticles were characterized on the basis of their anticipated peak at 405 nm using UV-Vis-NIR spectroscopy. Structural confirmation was evident from the characteristic X-ray diffraction (XRD) pattern, high-resolution transmission electron Microscopy (HRTEM) and the particle size analyzer. The Ag nanoparticles were of dimension 40 ± 5 nm and spherical in shape. The study mainly focused on using the confocal laser scanning microscope (CLSM) to examine the cytotoxic activities of fungal synthesized Ag nanoparticles on a human breast carcinoma cell line MCF7 cell, which featured remarkable vacuolation, thus indicating a potent cytotoxic activity.
SponsorDeanship of Scientific Research at King Saud University for its funding this Prolific Research group (PRG-1436-14).
Languageen
PublisherMDPI AG
Subjectsilver nanoparticles
Subjectcytotoxicity
Subjectbreast cancer
Subjectconfocal laser scanning microcopy
TitleEvaluation of the Cytotoxic Behavior of Fungal Extracellular Synthesized Ag Nanoparticles Using Confocal Laser Scanning Microscope
TypeArticle
Issue Number3
Volume Number17
ESSN1422-0067


Files in this item

Icon

This item appears in the following Collection(s)

Show simple item record