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AuthorAbubakar, Usman
AuthorAwaisu, Ahmed
AuthorKhan, Amer Hayat
AuthorAlam, Khurshid
Available date2024-01-24T09:33:35Z
Publication Date2023-11-01
Publication NameAntibiotics
Identifierhttp://dx.doi.org/10.3390/antibiotics12111600
CitationAbubakar, U., Awaisu, A., Khan, A. H., & Alam, K. (2023). Impact of COVID-19 Pandemic on Healthcare-Associated Infections: A Systematic Review and Meta-Analysis. Antibiotics, 12(11), 1600.‏
URIhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85178264319&origin=inward
URIhttp://hdl.handle.net/10576/51160
AbstractThis study investigated how the Coronavirus Disease 2019 (COVID-19) pandemic has affected the rate of healthcare-associated infections (HAIs). PubMed, Scopus and Google Scholar were searched to identify potentially eligible studies published from December 2019 to September 2022. A random effect model was used to determine the changes in the rate of HAIs during the pandemic. Thirty-seven studies, mostly from the United States (n = 13), were included. Fifteen studies described how the pandemic affected the rate of CLABSIs and CAUTIs, and eight of them showed a significant increase in CLABSIs. The risk of CLABSIs and CDIs was 27% (pooled odds ratio [OR]: 0.73; confidence interval [CI]: 0.61–0.89; p < 0.001) and 20% (pooled OR: 1.20; CI: 1.10–1.31; p < 0.001) higher during the pandemic compared to before the COVID-19 pandemic period, respectively. However, the overall risk of HAIs was unaffected by the pandemic (pooled OR: 1.00; 95 CI: 0.80–1.24; p = 0.990). Furthermore, there were no significant changes in the risk of CAUTIs (pooled OR: 1.01; 95 CI: 0.88–1.16; p = 0.890), and SSIs (pooled OR: 1.27; CI: 0.91–1.76; p = 0.16) between the two periods. The COVID-19 pandemic had no effect on the overall risk of HAIs among hospitalized patients, but an increased risk of CLABSIs and CDI were observed during the pandemic. Therefore, more stringent infection control and prevention measures and prudent interventions to promote the rational use of antibiotics are warranted across all healthcare facilities to reduce the burden of HAIs.
Languageen
PublisherMultidisciplinary Digital Publishing Institute (MDPI)
Subjectcatheter-associated urinary tract infection
central line-associated bloodstream infections
Clostridium difficile infection
COVID-19 pandemic
healthcare-associated infections
hospital-acquired pneumonia
surgical site infection
ventilator-associated pneumonia
TitleImpact of COVID-19 Pandemic on Healthcare-Associated Infections: A Systematic Review and Meta-Analysis
TypeArticle
Issue Number11
Volume Number12
dc.accessType Open Access


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