عرض بسيط للتسجيلة

المؤلفZaheer, Uzma
المؤلفHassain, Neeraja A.
المؤلفBanu, Shabeena
المؤلفMathew, Shilu
تاريخ الإتاحة2024-03-06T04:57:01Z
تاريخ النشر2021-01-01
اسم المنشورBiointerface Research in Applied Chemistry
المعرّفhttp://dx.doi.org/10.33263/BRIAC116.1482514852
معرّف المصادر الموحدhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85104870435&origin=inward
معرّف المصادر الموحدhttp://hdl.handle.net/10576/52708
الملخصThe tumor microenvironment is best described as the battleground for fighting cancer and the host immune system. Contrary to primitive beliefs that cancer growth and progression are solely dependent on cancer cells, recent studies suggest that the cancer cell mass environs also play a pivotal role. Active crosstalk between the tumor cells and their surrounding microenvironment permits their collusion to effectuate high cancer cell proliferation and metastasis. Tumors have been reported to actively recruit and alter immune cells' phenotypes and functions to either promote immune suppression or increase the tolerance towards tumor-associated antigens. Comprehending the part played by the tumor microenvironment in tumor progression and its mechanism of action paves the way for developing novel therapeutic approaches for a more personalized and efficient tumor microenvironment targeted anticancer treatment. This review elaborates on the nature and importance of the tumor microenvironment and the anti-cancer therapeutic strategies designed to target them. Furthermore, we discuss in-depth the employment of oncolytic viruses as nanomedicines for tumor microenvironment targeted anticancer therapy. This review also delineates the benefits of combining novel therapeutic approaches to existing treatment strategies to improve disease prognosis.
اللغةen
الناشرAMG Transcend Association
الموضوعNanomedicines
Nanoparticles
Oncolytic virus
Tumor microenvironment
Virotherapy
العنوانOncolytic viruses as nanomedicines against the tumor microenvironment
النوعArticle Review
الصفحات14825-14852
رقم العدد6
رقم المجلد11
ESSN2069-5837
dc.accessType Open Access


الملفات في هذه التسجيلة

Thumbnail

هذه التسجيلة تظهر في المجموعات التالية

عرض بسيط للتسجيلة