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المؤلفBansode, Rishipal R.
المؤلفRandolph, Priscilla
المؤلفAhmedna, Mohamed
المؤلفWilliams, Leonard L.
المؤلفYu, Jianmei
تاريخ الإتاحة2017-02-27T09:49:49Z
تاريخ النشر2015-03
اسم المنشورJournal of Medicinal Food
المعرّفhttp://dx.doi.org/ 10.1089/jmf.2014.0060
الاقتباسBansode Rishipal R., Randolph Priscilla, Ahmedna Mohamed, Williams Leonard L., and Yu Jianmei. Journal of Medicinal Food. March 2015, 18(3): 265-272
الرقم المعياري الدولي للكتاب1096-620X
معرّف المصادر الموحدhttp://hdl.handle.net/10576/5308
الملخصPeanut skin is a rich source of polyphenols, such as proanthocyanidins. Peanut skin proanthocyanidins mainly consist of a subgroup called procyanidins. Peanut-based procyanidins contain oligomers of both type A and type B procyanidins. Recent studies have shown that peanut skin extracts exert protection against hepatic steatosis induced on rats fed with a high-fat diet. Studies have shown that proanthocyanidins protect against cardiovascular diseases (CVDs). The mechanism of CVD protection and hypolipidemic effect of peanut skin procyanidins has been gradually revealed in recent years. Due to the high molecular weight of procyanidins, they are not readily absorbed through the gut barrier. It is hypothesized that procyanidins exert their effect by inhibiting the absorption of dietary lipid and chylomicron secretion by enterocytes. In this review, we aim to highlight the hypolipidemic effects of peanut skin polyphenols and discuss the various molecular mechanisms, with which the polyphenols may exert the lipid-lowering function observed by weighing the absorption characteristics as well as gene expression mechanism responsible for lipid homeostasis.
اللغةen
الناشرMary Ann Liebert, Inc.
الموضوعhypolipidemia
lipid metabolism
peanut skins
proanthocyanidins
العنوانBioavailability and hypolipidemic effects of peanut skin polyphenols
النوعArticle
الصفحات265-272
رقم العدد3
رقم المجلد18
ESSN1557-7600
dc.accessType Abstract Only


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