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المؤلفEl-Tanani, Mohamed
المؤلفNsairat, Hamdi
المؤلفAljabali, Alaa A.
المؤلفMatalka, Ismail I.
المؤلفAlkilany, Alaaldin M.
المؤلفTambuwala, Murtaza M.
تاريخ الإتاحة2024-04-29T08:23:54Z
تاريخ النشر2024-01-31
اسم المنشورExpert Opinion on Drug Delivery
المعرّفhttp://dx.doi.org/10.1080/17425247.2024.2311812
الاقتباسEl-Tanani, M., Nsairat, H., Aljabali, A. A., Matalka, I. I., Alkilany, A. M., & Tambuwala, M. M. (2024). Dual-loaded liposomal carriers to combat chemotherapeutic resistance in breast cancer. Expert Opinion on Drug Delivery,
الرقم المعياري الدولي للكتاب1742-5247
معرّف المصادر الموحدhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85184256023&origin=inward
معرّف المصادر الموحدhttp://hdl.handle.net/10576/54440
الملخصIntroduction: The resistance to chemotherapy is a significant hurdle in breast cancer treatment, prompting the exploration of innovative strategies. This review discusses the potential of dual-loaded liposomal carriers to combat chemoresistance and improve outcomes for breast cancer patients. Areas covered: This review discusses breast cancer chemotherapy resistance and dual-loaded liposomal carriers. Drug efflux pumps, DNA repair pathways, and signaling alterations are discussed as chemoresistance mechanisms. Liposomes can encapsulate several medicines and cargo kinds, according to the review. It examines how these carriers improve medication delivery, cancer cell targeting, and tumor microenvironment regulation. Also examined are dual-loaded liposomal carrier improvement challenges and techniques. Expert opinion: The use of dual-loaded liposomal carriers represents a promising and innovative strategy in the battle against chemotherapy resistance in breast cancer. This article has explored the various mechanisms of chemoresistance in breast cancer, emphasizing the potential of dual-loaded liposomal carriers to overcome these challenges. These carriers offer versatility, enabling the encapsulation and precise targeting of multiple drugs with different modes of action, a crucial advantage when dealing with the complexity of breast cancer treatment.
اللغةen
الناشرTaylor & Francis
الموضوعChemotherapy
immunomodulators
liposomes
nanocarriers
resistance
العنوانDual-loaded liposomal carriers to combat chemotherapeutic resistance in breast cancer
النوعArticle
رقم العدد2
رقم المجلد21
dc.accessType Abstract Only


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