عرض بسيط للتسجيلة

المؤلفAl Mana, Hassan
المؤلفAbdel Hadi, Hamad
المؤلفWilson, Godwin
المؤلفAlmaslamani, Muna A.
المؤلفAbu Jarir, Sulieman H.
المؤلفIbrahim, Emad
المؤلفEltai, Nahla O.
تاريخ الإتاحة2024-06-25T09:15:41Z
تاريخ النشر2024-03-01
اسم المنشورAntibiotics
المعرّفhttp://dx.doi.org/10.3390/antibiotics13030203
الاقتباسAl Mana, H.; Abdel Hadi, H.; Wilson, G.; Almaslamani, M.A.; Abu Jarir, S.H.; Ibrahim, E.; Eltai, N.O. Antimicrobial Resistance in Qatar: Prevalence and Trends before and Amidst the COVID-19 Pandemic. Antibiotics 2024, 13, 203. https://doi.org/10.3390/antibiotics13030203
معرّف المصادر الموحدhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85188731238&origin=inward
معرّف المصادر الموحدhttp://hdl.handle.net/10576/56231
الملخصAntimicrobial resistance (AMR) is a global healthcare challenge with substantial morbidity, mortality, and management costs. During the COVID-19 pandemic, there was a documented increase in antimicrobial consumption, particularly for severe and critical cases, as well as noticeable travel and social restriction measures that might influenced the spectrum of AMR. To evaluate the problem, retrospective data were collected on bacterial infections and antimicrobial susceptibility patterns in Qatar before and after the pandemic from 1 January 2019 to 31 December 2021, covering 53,183 pathogens isolated from reported infection episodes. The findings revealed a significant resistance pattern for extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-EBC), carbapenem-resistant Enterobacteriaceae (CR-EBC), and carbapenem-resistant Pseudomonas aeruginosa (CRPA), ciprofloxacin-resistant Salmonella and methicillin-resistant Staphylococcus aureus (MRSA). For correlation with social restrictions, ESBL-EBC and MRSA were positively correlated with changing patterns of international travel (ρ = 0.71 and 0.67, respectively; p < 0.05), while CRPA was moderately correlated with the number of COVID-19 hospitalized patients (ρ = 0.49; p < 0.05). CREBC and CRPA respiratory infections were associated with hospitalized patients (OR: 3.08 and 2.00, respectively; p < 0.05). The findings emphasize the challenges experienced during the COVID-19 pandemic and links to international travel, which probably will influence the local epidemiology of AMR that needs further surveillance and control strategies.
راعي المشروعThe study was conducted in accordance with the Declaration of Helsinki, and approved by the Institutional Review Board Ethics Committee of Hamad General Hospital, Medical Research Centre (MRC) (Protocol code: MRC-02-21-949) on 29 December 2021. and date of approval).” The study and collaboration were approved by the Medical Research Centre (MRC) of Hamad Medical Corporation (HMC), which abides by local and international research standards (Protocol: MRC-02-21-949). The study also received approval from the Ethical Committee and Institution Review Board of the MRC after observing data management and sharing standards, including limited access to nominated primary investigators, data anonymity, and governance. All shared data had no traced patients’ identification.
اللغةen
الناشرMDPI
الموضوعAMR
bacterial co-infection
COVID-19
hospital
Qatar
العنوانAntimicrobial Resistance in Qatar: Prevalence and Trends before and Amidst the COVID-19 Pandemic
النوعArticle
رقم العدد3
رقم المجلد13
ESSN2079-6382
dc.accessType Open Access


الملفات في هذه التسجيلة

Thumbnail

هذه التسجيلة تظهر في المجموعات التالية

عرض بسيط للتسجيلة